Hepatocellular carcinoma (HCC) remains not only a cause of a considerable part of
oncologic mortality, but also a diagnostic and therapeutic challenge for healthcare systems …

Hepatocellular carcinoma (HCC) has garnered considerable attention due to its morbidity
and mortality. Although the precise mechanisms underlying HCC tumorigenesis remain to …

Background Circular RNAs (circRNAs) are important for the process of cancer initiation and
progression. However, the role of circRNAs in hepatocellular carcinoma (HCC) remains …

Histopathologic grade of hepatocellular carcinoma (HCC) is an important predictor of early
recurrence and poor prognosis after curative treatments. This study aims to develop a …

Simple Summary Primary liver cancer is the third most common cause of cancer-related
deaths worldwide. Risk factors for primary liver cancer include chronic viral hepatitis B and C …

Purpose. One subtype of hepatocellular carcinoma (HCC), with cytokeratin 19 expression
(CK19+), has shown to be more aggressive and has a poor prognosis. However, CK19+ is …

Background The epigenetic regulators of cellular senescence, especially long non-coding
RNAs (lncRNAs), remain unclear. The expression levels of lncRNA were previously known …

Background Targeting protein kinase B (Akt) and its downstream signaling proteins are
promising options in designing novel and potent drug candidates against hepatocellular …

Background and aims The role of Alfa-fetoprotein (AFP) in the management of
hepatocellular carcinoma (HCC) is still debated, with differences in recommendations …

Hepatocellular carcinoma (HCC) is one of the most common types of cancer. The novel
sensitive biomarkers and therapeutic targets are urgently needed for the early diagnosis of …