Neuroinflammation in acute ischemic and hemorrhagic stroke

DL Alsbrook, M Di Napoli, K Bhatia, J Biller… - Current neurology and …, 2023 - Springer
Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

Acupuncture treatment for post-stroke depression: Intestinal microbiota and its role

H Jiang, S Deng, J Zhang, J Chen, B Li… - Frontiers in …, 2023 - frontiersin.org
Stroke-induced depression is a common complication and an important risk factor for
disability. Besides psychiatric symptoms, depressed patients may also exhibit a variety of …

[HTML][HTML] Potential regulatory effects of stem cell exosomes on inflammatory response in ischemic stroke treatment

N Chen, YL Wang, HF Sun, ZY Wang… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
The high incidence and disability rates of stroke pose a heavy burden on society.
Inflammation is a significant pathological reaction that occurs after an ischemic stroke …

Neuroinflammation and brain disease

A Bersano, J Engele, MKE Schäfer - BMC neurology, 2023 - Springer
Starting from the perspective of an immune-privileged site, our knowledge of the
inflammatory processes within the central nervous system has increased rapidly over the …

Engineered extracellular vesicles for ischemic stroke: A systematic review and meta-analysis of preclinical studies

P Li, R Yin, Y Chen, J Chang, L Yang, X Liu… - Journal of …, 2023 - Springer
Background This systematic review and meta-analysis aimed to evaluate the efficacy of
engineered extracellular vesicles (EEVs) in the treatment of ischemic stroke (IS) in …

[HTML][HTML] Microglial TNFR2 signaling regulates the inflammatory response after CNS injury in a sex-specific fashion

S Raffaele, E Thougaard, CCH Laursen, H Gao… - Brain, behavior, and …, 2024 - Elsevier
Microglia, the resident immune cells of the central nervous system (CNS), play a major role
in damage progression and tissue remodeling after acute CNS injury, including ischemic …

LXA4 attenuates perioperative neurocognitive disorders by suppressing neuroinflammation and oxidative stress

S Jiang, Q Wan, X Wang, L Di, X Li, R Kang, S Li… - International …, 2023 - Elsevier
Perioperative neurocognitive disorder (PND) is a common complication that increases
morbidity and mortality in elderly patients undergoing surgery. Abnormal microglia activation …

Sex and interferon gamma signaling regulate microglia migration in the adult mouse cortex in vivo

R Boghozian, S Sharma, K Narayana… - Proceedings of the …, 2023 - National Acad Sciences
Although microglia possess the unique ability to migrate, whether mobility is evident in all
microglia, is sex dependent, and what molecular mechanisms drive this, is not well …

Intermittent Fasting Induced Cerebral Ischemic Tolerance Altered Gut Microbiome and Increased Levels of Short-Chain Fatty Acids to a Beneficial Phenotype

B Chelluboina, T Cho, JS Park, SL Mehta… - Neurochemistry …, 2024 - Elsevier
Preconditioning-induced cerebral ischemic tolerance is known to be a beneficial adaptation
to protect the brain in an unavoidable event of stroke. We currently demonstrate that a short …

[HTML][HTML] MMP-3 Knockout Induces Global Transcriptional Changes and Reduces Cerebral Infarction in Both Male and Female Models of Ischemic Stroke

MH Hamblin, AC Boese, R Murad, JP Lee - International Journal of …, 2024 - mdpi.com
Ischemic stroke followed by reperfusion (IR) leads to extensive cerebrovascular injury
characterized by neuroinflammation and brain cell death. Inhibition of matrix …