IgA nephropathy (IgAN) is being recognized increasingly as a common form of
glomerulonephritis with progressive potential (17, 29, 42). Our initial goal here is briefly to …

Glomerulosclerosis and renal cysts in mice transgenic for the early region of SV40.
Considerable evidence indicates that genetic determinants play a major role in the …

Association of thin glomerular basement membrane with other glomerulopathies. In the
present study we assessed the prevalence of thin glomerular basement membrane (TGBM) …

Glomerulonephritis (GN*) is the most important cause of end-stage renal disease (ESRD)
leading to renal transplantation. In the United Kingdom and Ireland, 27% of renal transplant …

Immunoglobulin A nephropathy (IgAN) is the most frequently occurring primary
glomerulonephritis in Caucasian and Asian populations. Nonetheless, therapeutic …

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis
worldwide and a frequent cause of kidney failure. Currently, the diagnosis necessitates a …

A strong familial clustering of ESRD has been reported among African Americans,
suggesting that factors predisposing to renal failure, whether genetic, environmental, or …

Results A four-SNP model, rs11150612 (ITGAM-ITGAX), rs7634389 (ST6GAL1), rs2412971
(HORMAD2), and rs2856717 (HLA-DQ/DR), was selected as the best predictive model. The …

Inherited hemolytic-uremic syndrome (HUS) is unusual. We report the occurrence of HUS in
two siblings; one died at an early age while the other (the proband) has presented with three …

Genetic factors are considered to be involved in the initiation and progression of IgA
nephropathy (IgAN) on the basis of racial differences in the prevalence and familial …