IgA nephropathy (IgAN) is an autoimmune disorder which is believed to be non-monogenic.
We performed an exome-wide association study of 70 children with IgAN and 637 healthy …

We investigated whether polymorphisms of the renin-angiotensin system genes are involved
in IgA nephropathy in Japanese children. We identified the M235T polymorphism of the …

Background. There is growing evidence of genetic risk for susceptibility to IgA nephropathy.
Among several candidate genes related to immunological regulation in renal tissue, TGFB1 …

Abstract Background: IgA nephropathy (IgAN) is the most common type of primary
glomerulonephritis worldwide. Highly variable data for disease prevalence and reports of …

The continual development of potent immunosuppressive regimens has led to a decreased
incidence of acute rejection and improvement of short-term kidney allograft survival. In …

IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide
[1]. Up to 40% of IgAN patients progress to kidney failure within 20 years following diagnosis …

Hematuria and proteinuria are among the common reason why children are referred to a
pediatric nephrologist. The initial step in a child with hematuria is to establish the diagnosis …

Abstract Background. Familial aggregation of IgA nephropathy (IgAN) suggests that genetic
factors contribute to the development of this trait. Because clinical manifestations in IgAN …

Immunoglobulin (Ig) A nephropathy is one of the most common primary
glomerulonephritides worldwide causing end stage renal disease in up to 20–40% of …