Single-nucleotide polymorphisms in the class II region of the major histocompatibility complex in Japanese patients with immunoglobulin A nephropathy

F Akiyama, T Tanaka, R Yamada, Y Ohnishi… - Journal of human …, 2002 - nature.com
Immunoglobulin A nephropathy (IgAN) is a form of chronic glomerulonephritis of unknown
etiology and pathogenesis. Immunogenetic studies have not conclusively indicated that …

Immunoglobulin A nephropathy and ulcerative colitis: a focus on their pathogenesis

HM Trimarchi, A Iotti, R Iotti, EAR Freixas… - American journal of …, 2001 - karger.com
The immune response has largely been implicated in the pathogenesis of inflammatory
bowel disease (ulcerative colitis and Crohn's disease) and immunoglobulin A nephropathy …

Abnormalities of the IgA immune system in members of unrelated pedigrees from patients with IgA nephropathy

FP Schena, V Scivittaro, E Ranieri… - Clinical & …, 1993 - academic.oup.com
In the last few years many investigators have reported the recurrence of primary IgA
nephropathy (IgAN) or the presence of persistent microhaematuria and/or proteinuria in …

IL5RA and TNFRSF6B gene variants are associated with sporadic IgA nephropathy

XQ Liu, AD Paterson, N He… - Journal of the …, 2008 - journals.lww.com
Familial clustering and genome-wide linkage scans strongly support a genetic susceptibility
to familial IgA nephropathy (IgAN), but genetic factors that predispose to sporadic IgAN are …

The relevance of IgA deposits in vessel walls of clinically normal skin: a prospective study

RJ Hené, P Velthuis, A van de Wiel… - Archives of internal …, 1986 - jamanetwork.com
• Granular deposits of IgA are known to occur in the walls of superficial vessels in apparently
healthy skin of patients with primary IgA nephropathy, Henoch-Schönlein purpura, or …

DEFA gene variants associated with IgA nephropathy in a Chinese population

YY Qi, XJ Zhou, FJ Cheng, P Hou, L Zhu, SF Shi… - Genes & …, 2015 - nature.com
IgA nephropathy (IgAN) is a complex syndrome with high genetic heterogeneity. More
recently, a genome-wide association study (GWAS) from Southern Han population revealed …

Familial occurrence of primary glomerulonephritis: evidence for a role of genetic factors

F Scolari, A Amoroso, S Savoldi, E Prati… - Nephrology Dialysis …, 1992 - academic.oup.com
Chronic glomerulonephritis was diagnosed in 23 patients born in a small valley in Northern
Italy and in five additional patients with one parent or a more remote ancestor born in the …

Integrating human and rodent data to identify the genetic factors involved in chronic kidney disease

MR Garrett, MG Pezzolesi… - Journal of the American …, 2010 - journals.lww.com
The increasing numbers of patients with chronic kidney disease combined with no satisfying
interventions for preventing or curing the disease emphasize the need to better understand …

[HTML][HTML] Increased lifetime risk of ESRD in familial IgA nephropathy

M Shi, S Yu, Y Ouyang, Y Jin, Z Chen, W Wei… - Kidney International …, 2021 - Elsevier
Introduction Familial IgA nephropathy (IgAN) has been widely reported. However, its
clinicohistologic characteristics and long-term prognosis are not clear. Methods A total of …

Genome-wide association study of IgA nephropathy using 23 465 microsatellite markers in a Japanese population

S Saka, N Hirawa, A Oka, K Yatsu, T Hirukawa… - Journal of human …, 2015 - nature.com
Immunoglobulin A nephropathy (IgAN) is the most common form of primary
glomerulonephritis in many parts of the world. Although previous genome-wide association …