[HTML][HTML] Drug repurposing against KRAS mutant G12C: a machine learning, molecular docking, and molecular dynamics study
T Srisongkram, N Weerapreeyakul - International Journal of Molecular …, 2022 - mdpi.com
The Kirsten rat sarcoma viral G12C (KRASG12C) protein is one of the most common
mutations in non-small-cell lung cancer (NSCLC). KRASG12C inhibitors are promising for …
mutations in non-small-cell lung cancer (NSCLC). KRASG12C inhibitors are promising for …
[HTML][HTML] Squamous cell lung cancer
BR Sabbula, DP Gasalberti, F Anjum - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Objectives:< p> Identify the etiology of squamous cell lung cancer.</p>< p> Review the
appropriate history, physical, and evaluation of squamous cell lung cancer.</p>< p> Outline …
appropriate history, physical, and evaluation of squamous cell lung cancer.</p>< p> Outline …
[HTML][HTML] Discovery of drug targets and therapeutic agents based on drug repositioning to treat lung adenocarcinoma
Background Lung adenocarcinoma (LUAD) is the one of the most common subtypes in lung
cancer. Although various targeted therapies have been used in the clinical practice, the 5 …
cancer. Although various targeted therapies have been used in the clinical practice, the 5 …
[HTML][HTML] Current challenges and practical aspects of molecular pathology for non-small cell lung cancers
The continuing evolution of treatment options in thoracic oncology requires the pathologist to
regularly update diagnostic algorithms for management of tumor samples. It is essential to …
regularly update diagnostic algorithms for management of tumor samples. It is essential to …
Arterial chemotherapy for hepatocellular carcinoma in China: consensus recommendations
M Zhao, Z Guo, YH Zou, X Li, ZP Yan, MS Chen… - Hepatology …, 2024 - Springer
Hepatocellular carcinoma (HCC) is one of the most common malignancies and the third
leading cause of cancer-related deaths globally. Hepatic arterial infusion chemotherapy …
leading cause of cancer-related deaths globally. Hepatic arterial infusion chemotherapy …
Canakinumab versus placebo in combination with first-line pembrolizumab plus chemotherapy for advanced non–small-cell lung cancer: results from the CANOPY-1 …
PURPOSE The addition of checkpoint inhibitors to first-line treatment has prolonged survival
of patients with non–small-cell lung cancer (NSCLC), but prognosis remains poor, with new …
of patients with non–small-cell lung cancer (NSCLC), but prognosis remains poor, with new …
[HTML][HTML] Liquid biopsy in early-stage lung cancer: Current and Future Clinical Applications
O Vandekerckhove, K Cuppens, K Pat, B Du Pont… - Cancers, 2023 - mdpi.com
Simple Summary Early-stage disease non-small cell lung cancer has better outcomes than
advanced disease, but 5-year survival rates can drop to approximately 50% in cases of …
advanced disease, but 5-year survival rates can drop to approximately 50% in cases of …
[HTML][HTML] Immune checkpoint inhibitors in non-small cell lung cancer: From current perspectives to future treatments—A systematic review
A Olivares-Hernández, EG Del Portillo… - Annals of …, 2023 - ncbi.nlm.nih.gov
Background The introduction of immunotherapy in the treatment of non-small cell lung
cancer (NSCLC) has resulted in a radical change in patients' treatment responses and …
cancer (NSCLC) has resulted in a radical change in patients' treatment responses and …
[HTML][HTML] Circulating tumor DNA-based genomic profiling assays in adult solid tumors for precision oncology: recent advancements and future challenges
Simple Summary The use of liquid biopsy for tumor genomic profiling to identify genomic
biomarkers for targeted therapies has revolutionized the clinical practice in oncology …
biomarkers for targeted therapies has revolutionized the clinical practice in oncology …
Prognostic value of inflammatory and nutritional indexes among advanced NSCLC patients receiving PD‐1 inhibitor therapy
Q Fang, J Yu, W Li, J Luo, Q Deng… - Clinical and …, 2023 - Wiley Online Library
Though immunotherapy has to some extent improved the prognosis of patients with
advanced non‐small cell lung cancer (NSCLC), only a few patients benefit. Furthermore …
advanced non‐small cell lung cancer (NSCLC), only a few patients benefit. Furthermore …