Targeting apoptosis and autophagy following spinal cord injury: Therapeutic approaches to polyphenols and candidate phytochemicals

F Abbaszadeh, S Fakhri, H Khan - Pharmacological Research, 2020 - Elsevier
Spinal cord injury (SCI) is a neurological disorder associated with the loss of sensory and
motor function. Understanding the precise dysregulated signaling pathways, especially …

Butein in health and disease: A comprehensive review

G Padmavathi, NK Roy, D Bordoloi, F Arfuso, S Mishra… - Phytomedicine, 2017 - Elsevier
Background The risk of suffering from many chronic diseases seems to have made no
improvement despite the advancement in medications available in the modern world …

Anti-cancer effects of oxymatrine are mediated through multiple molecular mechanism (s) in tumor models

CE Halim, SL Xinjing, L Fan, JB Vitarbo, F Arfuso… - Pharmacological …, 2019 - Elsevier
Oxymatrine (OMT) is a quinolizidine alkaloid derived from the roots of the Sophora genus
plants. It has been widely used as a treatment for chronic hepatitis infections and …

[HTML][HTML] Butein suppresses PD-L1 expression via downregulating STAT1 in non-small cell lung cancer

L Zhao, W Zhang, F Luan, X Chen, H Wu, Q He… - Biomedicine & …, 2023 - Elsevier
PD-L1 (programmed cell death ligand 1) is frequently up-regulated in tumors and is critical
in tumor immune escape. In addition to antibodies that block the interaction between PD-L1 …

[HTML][HTML] An investigation on the therapeutic potential of butein, a tretrahydroxychalcone against human oral squamous cell carcinoma

D Bordoloi, J Monisha, M Roy… - Asian Pacific journal …, 2019 - ncbi.nlm.nih.gov
Background: Oral squamous cell carcinoma (OSCC) is one of the most predominant cancers
in India. With advances in the field of oncology, a number of therapies have emerged; …

Molecular mechanisms underlying chemopreventive potential of butein: Current trends and future perspectives

HS Tuli, R Joshi, D Aggarwal, G Kaur, J Kaur… - Chemico-Biological …, 2021 - Elsevier
Despite extensive efforts, cancer is still often considered as an incurable disease and
initiation of novel drug development programs is crucial to improve the prognosis and …

Potential application of zerumbone in the prevention and therapy of chronic human diseases

YP Singh, S Girisa, K Banik, S Ghosh, P Swathi… - Journal of Functional …, 2019 - Elsevier
Several active compounds from 'Mother Nature'have been found to be tailor-made
therapeutics for the better management of numerous chronic ailments, with fewer adverse …

[HTML][HTML] Anti-inflammatory activities of flavonoid derivates

Y Ysrafil, Z Sapiun, NS Slamet, F Mohamad… - ADMET and …, 2023 - hrcak.srce.hr
Background and purpose Flavonoids are a group of phytochemicals found abundantly in
various plants. Scientific evidence has revealed that flavonoids display potential biological …

Geranylation of chalcones by a fungal aromatic prenyltransferase

Q Ran, L Tao, X Zhou, SM Li, CM Yuan… - Journal of Agricultural …, 2023 - ACS Publications
Geranylated chalcones mainly exist in plants, and many of them have attracted attention
because of their diverse pharmacological and biological activities. Herein, we report …

Characterization of two microalgae consortia grown in industrial wastewater for biomass valorization

M Cinq-Mars, N Bourdeau, P Marchand… - Algal Research, 2022 - Elsevier
The use of microalgae-bacteria consortium coupled with biomass valorization is promising
for environmentally friendly and economical wastewater treatment. However, a significant …