The traditional complications of diabetes mellitus are well known and continue to pose a
considerable burden on millions of people living with diabetes mellitus. However, advances …

Executive summary The number of older people, including those living with dementia, is
rising, as younger age mortality declines. However, the age-specific incidence of dementia …

Aims/hypothesis The term prediabetes is used for individuals who have impaired glucose
metabolism whose glucose or HbA 1c levels are not yet high enough to be diagnosed as …

Importance Trends in type 2 diabetes show an increase in prevalence along with younger
age of onset. While vascular complications of early-onset type 2 diabetes are known, the …

Cognitive dysfunction is increasingly recognized as an important comorbidity of diabetes
mellitus. Different stages of diabetes-associated cognitive dysfunction exist, each with …

Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …

Considerable overlap has been identified in the risk factors, comorbidities and putative
pathophysiological mechanisms of Alzheimer disease and related dementias (ADRDs) and …

By 2017 estimates, diabetes mellitus affects 425 million people globally; approximately 90–
95% of these have type 2 diabetes. This narrative review highlights two domains of sex …

OBJECTIVE Type 2 diabetes (diabetes) is characterized by accelerated cognitive decline
and higher dementia risk. Controversy exists regarding the impact of metformin, which is …

Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …