Mucosal vaccines can effectively induce an immune response at the mucosal site and form
the first line of defense against microbial invasion. The induced mucosal immunity includes …

The oral route has long been recognized as the most preferred route for drug delivery as it
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …

Oral drug delivery systems have great potential to treat colorectal cancer (CRC). However,
the drug delivery efficiency is restricted by limited CRC-related intestine positioning and …

Zwitterionic polymers have emerged as promising trans-mucus nanocarriers due to their
superior antifouling properties. However, for pH-sensitive zwitterionic polymers, the effect of …

Colorectal cancer (CRC) is the second most common cause of cancer incidence worldwide.
Oral drug delivery systems (ODDS) have shown great promise for CRC therapy, but the …

Polysaccharides (PSA) have taken specific position among biomaterials for advanced
applications in medicine. Nevertheless, poor mechanical properties are known as the main …

In the last decade, additive manufacturing (AM) technologies have revolutionized how
healthcare provision is envisioned. The rapid evolution of these technologies has already …

Nutraceuticals have gained increasing attention over the last years due to their potential
value as therapeutic compounds formulated from natural sources. For instance, there is a …

Gastrointestinal mucus plays essential roles in modulating interactions between intestinal
lumen contents, including orally delivered drug carriers and the gut microbiome, and …

Mucus is a viscoelastic hydrogel that lubricates and protects mucosal tissues such as the
eyes, lung, gastrointestinal tract, and vagina. Nanoparticle-based drug delivery systems …