[HTML][HTML] The blood-brain barrier in aging and neurodegeneration
The blood-brain barrier (BBB) is vital for maintaining brain homeostasis by enabling an
exquisite control of exchange of compounds between the blood and the brain parenchyma …
exquisite control of exchange of compounds between the blood and the brain parenchyma …
New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation
N Zisapel - British journal of pharmacology, 2018 - Wiley Online Library
In mammals, a central circadian clock, located in the suprachiasmatic nuclei (SCN) of the
hypothalamus, tunes the innate circadian physiological rhythms to the ambient 24 h light …
hypothalamus, tunes the innate circadian physiological rhythms to the ambient 24 h light …
[HTML][HTML] Multimodal deep learning models for early detection of Alzheimer's disease stage
Most current Alzheimer's disease (AD) and mild cognitive disorders (MCI) studies use single
data modality to make predictions such as AD stages. The fusion of multiple data modalities …
data modality to make predictions such as AD stages. The fusion of multiple data modalities …
Trusted multi-view classification with dynamic evidential fusion
Existing multi-view classification algorithms focus on promoting accuracy by exploiting
different views, typically integrating them into common representations for follow-up tasks …
different views, typically integrating them into common representations for follow-up tasks …
Preparation of near-infrared AIEgen-active fluorescent probes for mapping amyloid-β plaques in brain tissues and living mice
Fibrillar aggregates of the amyloid-β protein (Aβ) are the main component of the senile
plaques found in brains of patients with Alzheimer's disease (AD). Development of probes …
plaques found in brains of patients with Alzheimer's disease (AD). Development of probes …
[HTML][HTML] Brain MRI analysis for Alzheimer's disease diagnosis using an ensemble system of deep convolutional neural networks
Alzheimer's disease is an incurable, progressive neurological brain disorder. Earlier
detection of Alzheimer's disease can help with proper treatment and prevent brain tissue …
detection of Alzheimer's disease can help with proper treatment and prevent brain tissue …
A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages
Neuroimaging has made it possible to measure pathological brain changes associated with
Alzheimer's disease (AD) in vivo. Over the past decade, these measures have been …
Alzheimer's disease (AD) in vivo. Over the past decade, these measures have been …
[HTML][HTML] Defining imaging biomarker cut points for brain aging and Alzheimer's disease
CR Jack Jr, HJ Wiste, SD Weigand, TM Therneau… - Alzheimer's & …, 2017 - Elsevier
Introduction Our goal was to develop cut points for amyloid positron emission tomography
(PET), tau PET, flouro-deoxyglucose (FDG) PET, and MRI cortical thickness. Methods We …
(PET), tau PET, flouro-deoxyglucose (FDG) PET, and MRI cortical thickness. Methods We …
Tau and Aβ imaging, CSF measures, and cognition in Alzheimer's disease
Alzheimer's disease (AD) is characterized by two molecular pathologies: cerebral β-
amyloidosis in the form of β-amyloid (Aβ) plaques and tauopathy in the form of neurofibrillary …
amyloidosis in the form of β-amyloid (Aβ) plaques and tauopathy in the form of neurofibrillary …
[HTML][HTML] Retinal amyloid pathology and proof-of-concept imaging trial in Alzheimer's disease
BACKGROUND. Noninvasive detection of Alzheimer's disease (AD) with high specificity and
sensitivity can greatly facilitate identification of at-risk populations for earlier, more effective …
sensitivity can greatly facilitate identification of at-risk populations for earlier, more effective …