[HTML][HTML] RAGE inhibitors in neurodegenerative diseases

VP Reddy, P Aryal, P Soni - Biomedicines, 2023 - mdpi.com
Nonenzymatic reactions of reducing sugars with primary amino groups of amino acids,
proteins, and nucleic acids, followed by oxidative degradations would lead to the formation …

[HTML][HTML] COVID-19 and Kidney: The Importance of Follow-Up and Long-Term Screening

V Rai - Life, 2023 - mdpi.com
Renal involvement and kidney injury are common in COVID-19 patients, and the symptoms
are more severe if the patient already has renal impairment. Renal involvement in COVID-19 …

[HTML][HTML] Urine-based detection of biomarkers indicative of chronic kidney disease in a patient cohort from Ghana

W Wruck, V Boima, L Erichsen, C Thimm… - Journal of Personalized …, 2022 - mdpi.com
Chronic kidney disease (CKD) is a global health burden with a continuously increasing
prevalence associated with an increasing incidence of diabetes and hypertension in aging …

[HTML][HTML] Significance of nitrosative stress and glycoxidation products in the diagnosis of COVID-19

B Wolszczak-Biedrzycka, J Dorf, J Matowicka-Karna… - Scientific Reports, 2024 - nature.com
Nitrosative stress promotes protein glycoxidation, and both processes can occur during an
infection with the SARS-CoV-2 virus. Therefore, the aim of this study was to assess selected …

Antiviral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and …

NR Dhanushkodi, S Prakash, A Quadiri… - The Journal of …, 2024 - journals.aai.org
SARS-CoV-2 variants of concern (VOCs) continue to evolve and reemerge with chronic
inflammatory long COVID sequelae, necessitating the development of anti-inflammatory …

[HTML][HTML] Methylglyoxal-Derived Nucleoside Adducts Drive Vascular Dysfunction in a RAGE-Dependent Manner

SWT Lai, S Bhattacharya, EDJ Lopez Gonzalez… - Antioxidants, 2024 - mdpi.com
Diabetic kidney disease (DKD) is a leading cause of death in patients with diabetes. An
early precursor to DKD is endothelial cell dysfunction (ECD), which often precedes and …

Pharmacological targets of SGLT2 inhibitors on IgA nephropathy and membranous nephropathy: a mendelian randomization study

X Lv, Y Shang, Y Ning, W Yu, J Wang - Frontiers in Pharmacology, 2024 - frontiersin.org
Introduction Emerging research suggests that sodium-glucose cotransporter 2 (SGLT2)
inhibitors may play a pivotal role in the treatment of primary glomerular diseases. This study …

Mechanisms of long COVID: An updated review

Y Liu, X Gu, H Li, H Zhang, J Xu - Chinese Medical Journal …, 2023 - mednexus.org
The coronavirus disease 2019 (COVID-19) pandemic has been ongoing for more than 3
years, with an enormous impact on global health and economies. In some patients …

[HTML][HTML] Quantitative Assessment of Intracellular Effectors and Cellular Response in RAGE Activation

V Deepu, V Rai, DK Agrawal - Archives of internal medicine …, 2024 - ncbi.nlm.nih.gov
The review delves into the methods for the quantitative assessment of intracellular effectors
and cellular response of Receptor for Advanced Glycation End products (RAGE), a vital …

[PDF][PDF] Molecular Mind Games: The Medicinal Action of Cyclodextrins in Neurodegenerative Diseases. Biomolecules 2023, 13, 666

SS Braga - 2023 - researchgate.net
Cyclodextrins are often used as molecular carriers for small active ingredients in medicine.
Recently, the intrinsic medicinal activity of some of these compounds has been under …