Bipolar depression: a major unsolved challenge

RJ Baldessarini, GH Vázquez, L Tondo - International journal of bipolar …, 2020 - Springer
Depression in bipolar disorder (BD) patients presents major clinical challenges. As the
predominant psychopathology even in treated BD, depression is associated not only with …

Pharmacological treatment of adult bipolar disorder

RJ Baldessarini, L Tondo, GH Vázquez - Molecular psychiatry, 2019 - nature.com
We summarize evidence supporting contemporary pharmacological treatment of phases of
BD, including: mania, depression, and long-term recurrences, emphasizing findings from …

Clinical phenotypes of psychosis in the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP)

CA Tamminga, EI Ivleva, MS Keshavan… - American Journal of …, 2013 - Am Psychiatric Assoc
Objective Developing categorical diagnoses that have biological meaning within the clinical
phenotype of psychosis (schizophrenia, schizoaffective disorder, and bipolar I disorder with …

Differences between bipolar disorder types 1 and 2 support the DSM two-syndrome concept

L Tondo, A Miola, M Pinna, M Contu… - International Journal of …, 2022 - Springer
Objective To compare characteristics of bipolar disorder patients diagnosed as DSM-5 types
I (BD-1) vs. II (BD-2). Methods We compared descriptive, psychopathological, and treatment …

Depression and mania in bipolar disorder

L Tondo, GH Vazquez… - Current …, 2017 - ingentaconnect.com
Background: Episode duration, recurrence rates, and time spent in manic and depressive
phases of bipolar disorder (BD) is not well defined for subtypes of the disorder. Methods: We …

Disability and its treatment in bipolar disorder patients

N Huxley, RJ Baldessarini - Bipolar disorders, 2007 - Wiley Online Library
Bipolar disorders (BPD) are major, lifelong psychiatric illnesses found in 2–5% of the
population. Prognosis for BPD was once considered relatively favorable, but contemporary …

Cognitive rehabilitation for bipolar disorder: An open trial for employed patients with residual depressive symptoms

T Deckersbach, AA Nierenberg… - CNS neuroscience & …, 2010 - Wiley Online Library
Bipolar disorder is characterized by recurrent episodes of depression and/or mania along
with interepisodic mood symptoms that interfere with psychosocial functioning. Despite …

The evolution of Kraepelin's nosological principles

S Heckers, KS Kendler - World Psychiatry, 2020 - Wiley Online Library
Emil Kraepelin developed a new psychiatric nosology in the eight editions of his textbook.
Previous papers have explored his construction of particular diagnoses, including dementia …

Mindfulnessbased cognitive therapy for nonremitted patients with bipolar disorder

T Deckersbach, BK Hölzel, LR Eisner… - CNS neuroscience & …, 2012 - Wiley Online Library
Introduction: Bipolar disorder is characterized by recurrent episodes of depression and/or
mania along with interepisodic mood symptoms that interfere with psychosocial functioning …

Bipolar depression: overview and commentary

RJ Baldessarini, E Vieta, JR Calabrese… - Harvard review of …, 2010 - journals.lww.com
Depressive phases are the most prevalent component of bipolar disorders, even with
modern treatment. Bipolar depressive morbidity is often misdiagnosed and is limited in …