Overview of PM2. 5 and health outcomes: focusing on components, sources, and pollutant mixture co-exposure

N Nan, Z Yan, Y Zhang, R Chen, G Qin, N Sang - Chemosphere, 2023 - Elsevier
PM 2.5 varies in source and composition over time and space as a complicated mixture.
Consequently, the health effects caused by PM 2.5 varies significantly over time and …

[HTML][HTML] Microglial Activation and Oxidative Stress in PM2.5-Induced Neurodegenerative Disorders

J Song, K Han, Y Wang, R Qu, Y Liu, S Wang, Y Wang… - Antioxidants, 2022 - mdpi.com
Fine particulate matter (PM2. 5) pollution remains a prominent environmental problem
worldwide, posing great threats to human health. The adverse effects of PM2. 5 on the …

[HTML][HTML] PM2. 5 exposure triggers cell death through lysosomal membrane permeabilization and leads to ferroptosis insensitivity via the autophagy dysfunction/p62 …

M Wei, G Bao, S Li, Z Yang, C Cheng, W Le - … and Environmental Safety, 2022 - Elsevier
PM2. 5 exposure can be associated with the onset of neurodegenerative diseases, with
oxidative stress-induced cellular homeostasis disruption and cell death as one of the main …

Fine particulate matter triggers α‐Synuclein fibrillization and Parkinson‐like neurodegeneration

X Yuan, Y Yang, C Liu, Y Tian, D Xia, Z Liu… - Movement …, 2022 - Wiley Online Library
Background The deposition of α‐synuclein (α‐Syn) in the brain is the pathological hallmark
of Parkinson's disease (PD). Epidemiological data indicate that exposure to fine particulate …

Neurotoxicity of the air-borne particles: from molecular events to human diseases

F Liu, C Liu, Y Liu, J Wang, Y Wang, B Yan - Journal of Hazardous Materials, 2023 - Elsevier
Exposure to PM 2.5 is associated with an increased incidence of CNS diseases in humans,
as confirmed by numerous epidemiological studies. Animal models have demonstrated that …

Long-term exposure of PM2. 5 components on the adults' depressive symptoms in China–Evidence from a representative longitudinal nationwide cohort

K Ju, L Lu, W Liao, C Yang, Z Xu, W Wang… - Science of The Total …, 2023 - Elsevier
In recent years, there is growing evidence that long-term exposure to fine particulate matter
(PM 2.5) is associated with depressive symptoms. However, little is known about the …

[HTML][HTML] Air quality improvement and cognitive function benefit: Insight from clean air action in China

X Hu, Z Nie, Y Ou, Z Qian, SE McMillin, HE Aaron… - Environmental …, 2022 - Elsevier
Introduction Epidemiological evidence suggests associations between long-term exposure
to air pollution and accelerated cognitive decline. China implemented a strict clean air action …

[HTML][HTML] Spatial-Temporal Evolution of Health Impact and Economic Loss upon Exposure to PM2.5 in China

X Sun, R Zhang, G Wang - … Journal of Environmental Research and Public …, 2022 - mdpi.com
Exposure to PM2. 5 can seriously endanger public health. Policies for controlling PM2. 5
need to consider health hazards under different circumstances. Unlike most studies on the …

[HTML][HTML] Organic extracts in PM2. 5 are the major triggers to induce ferroptosis in SH-SY5Y cells

CC Guo, Y Lyu, SS Xia, XK Ren, ZF Li, FJ Tian… - Ecotoxicology and …, 2023 - Elsevier
As a major air pollutant, PM2. 5 can induce apoptosis of nerve cells, causing impairment of
the learning and memory capabilities of humans and animals. Ferroptosis is a newly …

PM2. 5 exposure exacerbates seizure symptoms and cognitive dysfunction by disrupting iron metabolism and the Nrf2-mediated ferroptosis pathway

H Mei, D Wu, Z Yong, Y Cao, Y Chang, J Liang… - Science of The Total …, 2024 - Elsevier
In recent years, air pollution has garnered global attention due to its ability to traverse
borders and regions, thereby impacting areas far removed from the emission sources. While …