Basic principles of the virulence of Cryptococcus

O Zaragoza - Virulence, 2019 - Taylor & Francis
Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

Options and limitations in clinical investigation of bacterial biofilms

M Magana, C Sereti, A Ioannidis… - Clinical Microbiology …, 2018 - Am Soc Microbiol
Bacteria can form single-and multispecies biofilms exhibiting diverse features based upon
the microbial composition of their community and microenvironment. The study of bacterial …

Light-activated molecular machines are fast-acting broad-spectrum antibacterials that target the membrane

AL Santos, D Liu, AK Reed, AM Wyderka… - Science …, 2022 - science.org
The increasing occurrence of antibiotic-resistant bacteria and the dwindling antibiotic
research and development pipeline have created a pressing global health crisis. Here, we …

Innate humoral immune defences in mammals and insects: The same, with differences?

G Sheehan, A Garvey, M Croke, K Kavanagh - Virulence, 2018 - Taylor & Francis
The insect immune response demonstrates many similarities to the innate immune response
of mammals and a wide range of insects is now employed to assess the virulence of …

Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence …

G Janbon, KL Ormerod, D Paulet, EJ Byrnes III… - PLoS …, 2014 - journals.plos.org
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …

An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes

N Browne, M Heelan, K Kavanagh - Virulence, 2013 - Taylor & Francis
The insect immune response demonstrates a number of structural and functional similarities
to the innate immune system of mammals. As a result of these conserved features insects …

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

Spores as Infectious Propagules of Cryptococcus neoformans

R Velagapudi, YP Hsueh, S Geunes-Boyer… - Infection and …, 2009 - Am Soc Microbiol
Cryptococcus neoformans and Cryptococcus gattii are closely related pathogenic fungi that
cause pneumonia and meningitis in both immunocompromised and immunocompetent …

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

LE Cowen, SD Singh, JR Köhler… - Proceedings of the …, 2009 - National Acad Sciences
Invasive fungal infections are a leading cause of mortality among immunocompromised
individuals. Treatment is notoriously difficult with the limited armamentarium of antifungal …

Insect natural products and processes: new treatments for human disease

NA Ratcliffe, CB Mello, ES Garcia, TM Butt… - Insect biochemistry and …, 2011 - Elsevier
In this overview, some of the more significant recent developments in bioengineering natural
products from insects with use or potential use in modern medicine are described, as well as …