Virulence Potential and Treatment Options of Multidrug-Resistant (MDR) Acinetobacter baumannii

S Kumar, R Anwer, A Azzi - Microorganisms, 2021 - mdpi.com
Acinetobacter baumannii is an opportunistic pathogen which is undoubtedly known for a
high rate of morbidity and mortality in hospital-acquired infections. A. baumannii causes life …

In vitro and in vivo toxicity and antibacterial efficacy of melittin against clinical extensively drug-resistant bacteria

P Askari, MH Namaei, K Ghazvini… - BMC Pharmacology and …, 2021 - Springer
Background Melittin is one of the most studied antimicrobial peptides, and several in vitro
experiments have demonstrated its antibacterial efficacy. However, there is evidence …

Some suggestions from PK/PD principles to contain resistance in the clinical setting—focus on ICU patients and gram-negative strains

C Adembri, A Novelli, S Nobili - Antibiotics, 2020 - mdpi.com
The containment of the phenomenon of resistance towards antimicrobials is a priority,
especially in preserving molecules acting against Gram-negative pathogens, which …

Synergistic combination of carvedilol, amlodipine, amitriptyline, and antibiotics as an alternative treatment approach for the susceptible and multidrug-resistant A …

E Ugurel, D Turgut-Balik - European Journal of Clinical Microbiology & …, 2023 - Springer
We evaluated in vitro activity of 13 drugs used in the treatment of some non-communicable
diseases via repurposing to determine their potential use in the treatment of Acinetobacter …

Uropathogenic Escherichia coli endeavors: an insight into the characteristic features, resistance mechanism, and treatment choice

V Arafi, A Hasani, J Sadeghi, M Varshochi… - Archives of …, 2023 - Springer
Uropathogenic Escherichia coli (UPEC) are the strains diverted from the intestinal status and
account mainly for uropathogenicity. This pathotype has gained specifications in structure …

A carbapenem-resistant Acinetobacter baumannii outbreak associated with a polymyxin shortage during the COVID pandemic: an in vitro and biofilm analysis of …

V Chaiben, CH Yamada, JP Telles… - Journal of …, 2022 - academic.oup.com
Background During the COVID-19 pandemic, the burden of nosocomial infections caused by
MDR pathogens has caused a shortage of polymyxins. Thus, we evaluated the in vitro …

Assessing clinical potential of old antibiotics against severe infections by multi-drug-resistant gram-negative bacteria using in silico modelling

P Paranos, S Vourli, S Pournaras, J Meletiadis - Pharmaceuticals, 2022 - mdpi.com
In the light of increasing antimicrobial resistance among gram-negative bacteria and the lack
of new more potent antimicrobial agents, new strategies have been explored. Old antibiotics …

Potentials of organic tellurium-containing compound AS101 to overcome carbapenemase-producing Escherichia coli

TY Yang, WC Hung, TH Tsai, PL Lu, SF Wang… - Journal of Microbiology …, 2023 - Elsevier
Background The issue of carbapenem-resistant Escherichia coli was aggravated yearly. The
previous studies reported the varied but critical epidemiology of carbapenem-resistant E …

Novel Pyrazoles As Potent Growth Inhibitors of Staphylococci, Enterococci and Acinetobacter Baumannii Bacteria

I Alkhaibari, HR Kc, DH Angappulige… - Future Medicinal …, 2022 - Taylor & Francis
Background: Methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci
and Acinetobacter baumannii cause serious antibiotic-resistant infections. Finding new …

[HTML][HTML] In vitro activity of riparin III in combination with antimicrobials against multidrug-resistant clinical isolates of Staphylococcus aureus and Acinetobacter …

JB Oliveira-Júnior, FCG de Lima, EF Firmo… - Phytomedicine Plus, 2023 - Elsevier
S. aureus and A. baumannii are among the main bacterial species responsible for several
infections worldwide due to the different resistance and virulence mechanisms, which can …