In vivo gene delivery mediated by non-viral vectors for cancer therapy

R Mohammadinejad, A Dehshahri… - Journal of Controlled …, 2020 - Elsevier
Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …

A review on the synthesis of graft copolymers of chitosan and their potential applications

D Kumar, S Gihar, MK Shrivash, P Kumar… - International Journal of …, 2020 - Elsevier
Chitosan is an antimicrobial, biodegradable and biocompatible natural polymer,
commercially derived from the partial deacetylation of chitin. Currently modified chitosan has …

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

K Mahmoud, S Swidan, M El-Nabarawi… - Journal of …, 2022 - Springer
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing

X Zhou, Y Guo, K Yang, P Liu, J Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …

Multi-spectroscopic investigation, molecular docking and molecular dynamic simulation of competitive interactions between flavonoids (quercetin and rutin) and …

NA Alsaif, TA Wani, AH Bakheit, S Zargar - International Journal of …, 2020 - Elsevier
The main mechanism for drug-drug interaction is displacement reaction of ligands from their
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …

Recent advances in targeted nanomedicine as promising antitumor therapeutics

S Hejmady, R Pradhan, A Alexander, M Agrawal… - Drug discovery today, 2020 - Elsevier
Highlights•Nanocarriers with the ability to target tumors are being increasingly explored.•
Nanomedicine aid in maintaining a balance between efficacy and toxicity.•Recent advances …

Safranal prevents liver cancer through inhibiting oxidative stress and alleviating inflammation

Y Abdalla, A Abdalla, AA Hamza, A Amin - Frontiers in Pharmacology, 2022 - frontiersin.org
Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural
products and their derived biomolecules are potential resources to mine for novel anti …

Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis

P Allawadhi, V Singh, K Govindaraj, I Khurana… - Carbohydrate …, 2022 - Elsevier
Polysaccharides are biopolymers distinguished by their complex secondary structures
executing various roles in microorganisms, plants, and animals. They are made up of long …

Co-administration of iRGD with sorafenib-loaded iron-based metal-organic framework as a targeted ferroptosis agent for liver cancer therapy

X Liu, X Zhu, X Qi, X Meng, K Xu - International Journal of …, 2021 - Taylor & Francis
Purpose Hepatocellular carcinoma (HCC) is one of the most common fatal cancers, with no
curative therapy available. The concept of ferroptosis is attracting increasing attention in …

[HTML][HTML] Green nanotechnology-based gold nanomaterials for hepatic cancer therapeutics: a systematic review

H Barabadi, TJ Webster, H Vahidi… - Iranian journal of …, 2020 - ncbi.nlm.nih.gov
The objective of the current study was to systematically review the in-vitro anticancer activity
of green synthesized gold nanoparticles (AuNPs) against hepatic cancer cells. The articles …