Small nucleolar RNAs (SnoRNAs) are a class of non-coding RNAs divided into two classes:
C/D box snoRNAs and H/ACA box snoRNAs. The canonical function of C/D box and H/ACA …

The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …

Transcribing RNA Polymerase II interacts with multiple factors that orchestrate maturation
and stabilisation of messenger RNA. For the majority of noncoding RNAs, the polymerase …

Glioblastoma (GBM) ranks among the most lethal of human cancers, containing glioma stem
cells (GSCs) that display therapeutic resistance. Here, we report that the lncRNA INHEG is …

Telomerase is the essential reverse transcriptase required for linear chromosome
maintenance in most eukaryotes. Telomerase supplements the tandem array of simple …

Dysregulated translation is a common feature of cancer. Uncovering its governing factors
and underlying mechanism are important for cancer therapy. Here, we report that enhancer …

Nm (2′-O-methylation) is one of the most common modifications in the RNA world. It has
the potential to influence the RNA molecules in multiple ways, such as structure, stability …

Neurodegenerative diseases (NDs) are becoming increasingly prevalent in the world, with
an aging population. In the last few decades, due to the devastating nature of these …

Abstract Background Small nucleolar RNAs (snoRNAs) are abundant noncoding RNAs best
known for their involvement in ribosomal RNA maturation. In mammals, most expressed …

Abstract The transcription of 18S, 5.8 S, and 18S rRNA genes (45S rDNA), cotranscriptional
processing of pre-rRNA, and assembly of mature rRNA with ribosomal proteins are the …