Background: In Ethiopia, where malaria parasite and Schistosoma mansoni infections are
coendemic, the general public is quite vulnerable to both malaria and S. mansoni infections …

In interferon-γ activated human macrophages, GTP-cyclohydrolase 1 catalyses the
conversion of guanosine triphosphate to 7, 8-dihydroneopterin triphosphate, which is …

Background: Malaria-related deaths could be prevented if prompt diagnosis and prognostic
biomarkers are available to allow rapid adequate treatment. Understanding of the …

In Ethiopia where malaria parasite and Schistosoma mansoni infections are coendemic, the
general population is quite vulnerable both to malaria and Schistosoma mansoni infections …

An inappropriate immune response to parasite infection is one of the primary drivers of
malaria pathogenesis. Regulatory T cells (Tregs), an important subset of CD 4+ T cells, can …

Naturally acquired immunity to malaria is Plasmodium species strain-and variant-specific. It
is non-sterile and short-lived therefore requiring repeated exposure. These protective …

Cerebral malaria (CM) and severe malarial anemia (SMA) remain drivers of morbidity and
mortality due to Plasmodium falciparum infection in children in Sub-Saharan Africa. There …

El FNT-α y la IL-10 son citocinas reguladoras que intervienen en los procesos
inmunológicos y actúan como mediadores proinflamatorios y antiinflamatorios …

The development of an efficacious P. falciparum malaria vaccine remains a top priority. Pre-
erythrocytic vaccine efforts have traditionally focussed on two well-known antigens, CSP and …

Introduction and aim of the study: Artery-to-artery atherothromboembolic ischaemic insults in
the carotid artery domain may be determined by vulnerable (high-risk) features of carotid …