The way sporadic Parkinson's disease (PD) is perceived has undergone drastic changes in
recent decades. For a long time, PD was considered a brain disease characterized by motor …

Glutathione (GSH) is a tripeptide, which has many biological roles including protection
against reactive oxygen and nitrogen species. The primary goal of this paper is to …

Reactive oxygen species (ROS) are an unenviable part of aerobic life. Their steady-state
concentration is a balance between production and elimination providing certain steady …

The indiscriminate use of plastic has greatly increased microplastic contamination risk in the
marine environment. Microplastics can affect all marine life via the food web, from primary …

Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-
spectrum applicability to prevent dreadful diseases such as cardiovascular disease …

The Blood Brain Barrier (BBB) is a specialized vascular structure tightly regulating central
nervous system (CNS) homeostasis. Endothelial cells are the central component of the BBB …

Despite the widespread interest in direct neuronal reprogramming, the mechanisms
underpinning fate conversion remain largely unknown. Our study revealed a critical time …

Reactive oxygen species, such as superoxide and hydrogen peroxide, are generated in all
cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can …

Despite improvements in awareness and treatment of type II diabetes mellitus (TIIDM), this
disease remains a major source of morbidity and mortality worldwide, and prevalence …

Nonenzymatic lipid oxidation is usually viewed as deleterious. But if this is the case, then
why does it occur so frequently in cells? Here we review the mechanisms of membrane …