NAD (P) H: quinone acceptor oxidoreductase 1 (NQO1) is a widely-distributed FAD-
dependent flavoprotein that promotes obligatory 2-electron reductions of quinones …

Intracerebral hemorrhage (ICH) is one of the most lethal stroke subtypes. Despite the high
morbidity and mortality associated with ICH, its pathophysiology has not been investigated …

Air pollution is consistently linked with elevations in cardiovascular disease (CVD) and CVD-
related mortality. Particulate matter (PM) is a critical factor in air pollution-associated CVD …

The Nrf2-Keap1-ARE pathway is the principal regulator of antioxidant and phase II
detoxification genes. Its activation increases the expression of antioxidant and cytoprotective …

Health and wellbeing are significantly impaired by alcoholic liver disease (ALD), and
although some lactic acid bacteria strains have been shown previously to relieve ALD …

Liver injury is a common pathological process, which can result in fatty liver, cirrhosis,
fibrosis and even cancer. Polysaccharides isolated from plants have been regarded as an …

Numerous epidemiological studies have consistently linked the presence of chronic
obstructive pulmonary disease (COPD) to the development of lung cancer, independently of …

Atherosclerosis remains the underlying process responsible for cardiovascular diseases
and the high mortality rates associated. This chronic inflammatory disease progresses with …

Neurodegenerative disorders affect more than fifty million Americans each year and
represent serious health threats as the population ages. Neuroinflammation and oxidative …

Mitochondrially generated reactive oxygen species are involved in a myriad of signaling and
damaging pathways in different tissues. In addition, mitochondria are an important target of …