[HTML][HTML] Reconnoitring signaling pathways and exploiting innovative approaches tailoring multifaceted therapies for skin cancer

D Datta, S Sultana, J Strauss, A Puri, SP Bandi… - International Journal of …, 2024 - Elsevier
Nowadays, skin cancer is widespread just like a varied malignant cancer which can cause
serious health issues. Skin cancer, which encompasses malignant melanoma, basal cell …

[HTML][HTML] Cyclodextrin encapsulation enabling the anticancer repositioning of disulfiram: Preparation, analytical and in vitro biological characterization of the inclusion …

BM Benkő, G Tóth, D Moldvai, S Kádár, E Szabó… - International Journal of …, 2024 - Elsevier
Drug repositioning is a high-priority and feasible strategy in the field of oncology research,
where the unmet medical needs are continuously unbalanced. Disulfiram is a potential non …

[HTML][HTML] 1H and 31P Magnetic Resonance Spectroscopic Metabolomic Imaging: Assessing Mitogen-Activated Protein Kinase Inhibition in Melanoma

PK Gupta, S Orlovskiy, F Arias-Mendoza, DS Nelson… - Cells, 2024 - mdpi.com
The MAPK signaling pathway with BRAF mutations has been shown to drive the
pathogenesis of 40–60% of melanomas. Inhibitors of this pathway's BRAF and MEK …

ACSS2 enables melanoma cell survival and tumor metastasis by negatively regulating the Hippo pathway

B Zhang, Q Zhu, D Qu, M Zhao, J Du… - Frontiers in Molecular …, 2024 - frontiersin.org
Introduction Acetyl-CoA synthetase 2 (ACSS2), one of the enzymes that catalyze the
conversion of acetate to acetyl-CoA, has been proved to be an oncogene in various cancers …

Autophagy as a targeted therapeutic approach for skin cancer: Evaluating natural and synthetic molecular interventions

L Ali, AH Roky, AK Azad, AH Shaikat… - Cancer Pathogenesis …, 2024 - mednexus.org
Skin cancer, a prevalent malignancy worldwide, poses significant health concerns owing to
its increasing incidence. Autophagy, a natural cellular process, is a pivotal event in skin …

[HTML][HTML] Daphnetin, a coumarin with anticancer potential against human melanoma: in vitro study of its effective combination with selected cytostatic drugs

P Wróblewska-Łuczka, A Góralczyk, JJ Łuszczki - Cells, 2023 - mdpi.com
(1) The treatment of metastatic or drug-resistant melanoma is still a significant therapeutic
problem. The aim of this study was to evaluate the anticancer potential of daphnetin (7, 8 …

Multifunctional polypeptide-based polymersome for chemophotothermal therapy of melanoma in vitro and in vivo

M Hasannia, K Abnous, SM Taghdisi… - Journal of Drug Delivery …, 2024 - Elsevier
To date, combination therapy using chemo-photothermal therapy (Ch-PTT) has attracted
tremendous interest due to its efficient ablation of cancerous cells. Furthermore, there are …

[HTML][HTML] Silver Complexes of Miconazole and Metronidazole: Potential Candidates for Melanoma Treatment

M Fabijańska, AJ Rybarczyk-Pirek… - International Journal of …, 2024 - mdpi.com
Melanoma, arguably the deadliest form of skin cancer, is responsible for the majority of skin-
cancer-related fatalities. Innovative strategies concentrate on new therapies that avoid the …

[HTML][HTML] Melanoma as Subsequent Primary Malignancy in Hematologic Cancer Survivors—A Literature Review

SR Halmágyi, L Ungureanu, II Trufin… - Journal of Clinical …, 2024 - mdpi.com
The occurrence of second primary malignancies is becoming increasingly important among
cancer survivors. Melanoma, an aggressive neoplasm originating from the melanocytes, is …

Exploring the Multifaceted Effects of Silymarin on Melanoma: Focusing on the Role of Lipid-Based Nanocarriers

F Arghidash, MJ Javid-Naderi, F Gheybi… - Journal of Drug Delivery …, 2024 - Elsevier
Efforts to find effective therapeutic solutions for various types of cancer, including melanoma,
have increased due to the rising incidence and mortality rates associated with these …