Plugging the leak of nanoparticles by interfacial polymer adsorption enables an efficient protein and peptide encapsulation
Q Huo, Y Gao, W Wu, S Hu, E Dong… - Advanced Functional …, 2024 - Wiley Online Library
Encapsulation is a promising technology to enhance the pharmacokinetic properties of
proteins and peptides, particularly addressing their short half‐life. Despite its potential, this …
proteins and peptides, particularly addressing their short half‐life. Despite its potential, this …
Dual stimuli-responsive dendronized prodrug derived from poly (oligo-(ethylene glycol) methacrylate)-based copolymers for enhanced anti-cancer therapeutic effect
In this study, we developed an enzyme-and pH-responsive dendronized poly (oligo-
(ethylene glycol) methacrylate)(pOEGMA)-doxorubicin (DOX) polymeric prodrug, which …
(ethylene glycol) methacrylate)(pOEGMA)-doxorubicin (DOX) polymeric prodrug, which …
Facile preparation of pH-responsive PEGylated prodrugs for activated intracellular drug delivery
Y Song, D Li, J He, M Zhang, P Ni - Chinese Chemical Letters, 2019 - Elsevier
PEGylated prodrug, covalent attaching polyethylene glycol (PEG) polymer chains to
therapeutic drugs, is one of the most promising techniques to improve the water-solubility …
therapeutic drugs, is one of the most promising techniques to improve the water-solubility …
Targeted Delivery of Anticancer Therapeutics with Polymers by Harnessing Tumor Microenvironment Acidity
J Shi, B Ma, Y Zhang, H Yong, Z Li, X Huang… - Chemistry of …, 2023 - ACS Publications
Cancer therapy is a global biomedical challenge, and a number of promising anticancer
therapeutics, such as small-molecule drugs, proteins, nucleic acids, photothermal agents …
therapeutics, such as small-molecule drugs, proteins, nucleic acids, photothermal agents …
Layer‐by‐layer assembly for surface tethering of thin‐hydrogel films: Design strategies and applications
Manipulation and engineering of the surfaces has a key role in improving the materials
properties. Anchoring of thin hydrogels on the materials surface is one of the recently …
properties. Anchoring of thin hydrogels on the materials surface is one of the recently …
Controlled Ring-Opening Polymerization of Macrocyclic Monomers Based on Ring-Opening/Ring-Closing Cascade Reaction
W Chen, C Guo, H Ding, X Yang… - Journal of the American …, 2023 - ACS Publications
The development of a controlled ring-opening polymerization (ROP) method for synthesizing
backbone-functionalized and sequence-controlled polymers with well-defined architectures …
backbone-functionalized and sequence-controlled polymers with well-defined architectures …
Stimulation–inhibition of protein release from alginate hydrogels using electrochemically generated local pH changes
The electrochemically controlled release of proteins was studied in a Ca2+-cross-linked
alginate hydrogel deposited on an electrode surface. The electrochemical oxidation of …
alginate hydrogel deposited on an electrode surface. The electrochemical oxidation of …
Ultrasound-induced drug release from stimuli-responsive hydrogels
TJ Yeingst, JH Arrizabalaga, DJ Hayes - Gels, 2022 - mdpi.com
Stimuli-responsive hydrogel drug delivery systems are designed to release a payload when
prompted by an external stimulus. These platforms have become prominent in the field of …
prompted by an external stimulus. These platforms have become prominent in the field of …
Manganese-zeolitic imidazolate frameworks-90 with high blood circulation stability for MRI-guided tumor therapy
Zeolitic imidazolate frameworks (ZIFs) as smart drug delivery systems with
microenvironment-triggered release have attracted much attention for tumor therapy …
microenvironment-triggered release have attracted much attention for tumor therapy …
Optimizing the self‐assembly of conjugated polymers and small molecules through structurally programmed non‐covalent control
WJ Mullin, SA Sharber… - Journal of Polymer …, 2021 - Wiley Online Library
Organic conjugated polymers and oligomers are key electronic materials for applications
such as transistors, photovoltaics, and light emitting devices due to their potential for solution …
such as transistors, photovoltaics, and light emitting devices due to their potential for solution …