Galectins are carbohydrate-binding proteins that are involved in many physiological
functions, such as inflammation, immune responses, cell migration, autophagy and …

All cells in the human body are covered by a dense layer of sugars and the proteins and
lipids to which they are attached, collectively termed the “glycocalyx.” For decades, the …

Synthetic vesicles have been assembled and coassembled from phospholipids, their
modified versions, and other single amphiphiles into liposomes, and from block copolymers …

Glioblastoma multiforme (GBMs) are recurrent lethal brain tumours. Recurrent GBMs often
exhibit mesenchymal, stem-like phenotypes that could explain their resistance to therapy …

Osteoarthritis (OA) has long been viewed as a degenerative disease of cartilage, but
accumulating evidence indicates that inflammation has a critical role in its pathogenesis. In …

Gold nanoparticles (AuNPs), which have been widely used for the delivery of
photosensitizers for photodynamic therapy (PDT) of cancer, can be dispersed in aqueous …

Aberrant glycan epitopes are a classic hallmark of malignant transformation, yet their full
clinical potential in cancer diagnostics and therapeutics is yet to be realized. This is partly …

Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many
biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task …

The invasion of cancer is brought about by continuous interaction of malignant cells with
their surrounding tissue microenvironment. Investigating the remodeling of local …

Heterogeneity in phenotypes of malignantly transformed cells and aberrant glycan
expression on their surface are two prominent hallmarks of cancers that have hitherto not …