Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system?
M Desforges, A Le Coupanec, P Dubeau, A Bourgouin… - viruses, 2019 - mdpi.com
Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases.
However, in vulnerable populations, such as newborns, infants, the elderly and immune …
However, in vulnerable populations, such as newborns, infants, the elderly and immune …
Molecular and metabolic heterogeneity of astrocytes and microglia
Astrocytes and microglia are central players in a myriad of processes in the healthy and
diseased brain, ranging from metabolism to immunity. The crosstalk between these two cell …
diseased brain, ranging from metabolism to immunity. The crosstalk between these two cell …
[HTML][HTML] The neuropsychiatric manifestations of COVID-19: Interactions with psychiatric illness and pharmacological treatment
The recent outbreak of the corona virus disease (COVID-19) has had major global impact.
The relationship between severe acute respiratory syndrome coronavirus (SARS-CoV-2) …
The relationship between severe acute respiratory syndrome coronavirus (SARS-CoV-2) …
Osteopontin/secreted phosphoprotein‐1 harnesses glial‐, immune‐, and neuronal cell ligand‐receptor interactions to sense and regulate acute and chronic …
A Yim, C Smith, AM Brown - Immunological reviews, 2022 - Wiley Online Library
Osteopontin (OPN) also known by its official gene designation secreted phosphoprotein‐1
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …
(SPP1) is a fascinating, multifunctional protein expressed in a number of cell types that …
Human coronaviruses: viral and cellular factors involved in neuroinvasiveness and neuropathogenesis
M Desforges, A Le Coupanec, JK Stodola… - Virus research, 2014 - Elsevier
Among the various respiratory viruses infecting human beings, coronaviruses are important
pathogens, which usually infect the upper respiratory tract, where they are mainly associated …
pathogens, which usually infect the upper respiratory tract, where they are mainly associated …
Neuroinvasive and neurotropic human respiratory coronaviruses: potential neurovirulent agents in humans
M Desforges, A Le Coupanec, É Brison… - Infectious Diseases and …, 2014 - Springer
In humans, viral infections of the respiratory tract are a leading cause of morbidity and
mortality worldwide. Several recognized respiratory viral agents have a neuroinvasive …
mortality worldwide. Several recognized respiratory viral agents have a neuroinvasive …
Calcium ions in neuronal degeneration
U Wojda, E Salinska, J Kuznicki - IUBMB life, 2008 - Wiley Online Library
Abstract Neuronal Ca2+ homeostasis and Ca2+ signaling regulate multiple neuronal
functions, including synaptic transmission, plasticity, and cell survival. Therefore …
functions, including synaptic transmission, plasticity, and cell survival. Therefore …
HIV infection and latency induce a unique metabolic signature in human macrophages
P Castellano, L Prevedel, S Valdebenito… - Scientific reports, 2019 - nature.com
Currently, a major barrier to curing HIV infection is the generation of tissue-associated, non-
replicating, long-lasting viral reservoirs that are refractory to therapy and can be reactivated …
replicating, long-lasting viral reservoirs that are refractory to therapy and can be reactivated …
Adriamycin-induced, TNF-α-mediated central nervous system toxicity
The clinical effectiveness of adriamycin (ADR), a potent chemotherapeutic, is known to be
limited by severe cardiotoxic side effects. However, the effect of ADR on brain tissue is not …
limited by severe cardiotoxic side effects. However, the effect of ADR on brain tissue is not …
Synaptic dysfunction in the hippocampus accompanies learning and memory deficits in human immunodeficiency virus type-1 Tat transgenic mice
S Fitting, BM Ignatowska-Jankowska, C Bull… - Biological …, 2013 - Elsevier
BACKGROUND: Human immunodeficiency virus (HIV) associated neurocognitive disorders
(HAND), including memory dysfunction, continue to be a major clinical manifestation of HIV …
(HAND), including memory dysfunction, continue to be a major clinical manifestation of HIV …