Targeted therapy for head and neck cancer: signaling pathways and clinical studies
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
Antisense oligonucleotides targeting angiogenic factors as potential cancer therapeutics
Cancer is one of the leading causes of death worldwide, and conventional cancer therapies
such as surgery, chemotherapy, and radiotherapy do not address the underlying molecular …
such as surgery, chemotherapy, and radiotherapy do not address the underlying molecular …
Tumor detection using magnetosome nanoparticles functionalized with a newly screened EGFR/HER2 targeting peptide
Z Xiang, X Yang, J Xu, W Lai, Z Wang, Z Hu, J Tian… - Biomaterials, 2017 - Elsevier
A novel peptide (P75) targeting EGFR and HER2 is successfully screened from a one-bead-
one-compound (OBOC) library containing approximately 2× 10 5 peptides built with the aid …
one-compound (OBOC) library containing approximately 2× 10 5 peptides built with the aid …
Electroporation in head-and-neck cancer: an innovative approach with immunotherapy and nanotechnology combination
S Pisani, G Bertino, A Prina-Mello, LD Locati… - Cancers, 2022 - mdpi.com
Simple Summary This review provides a summary of the head-and-neck squamous cell
carcinoma (HNSCC) biological characteristics and its current treatments. Furthermore …
carcinoma (HNSCC) biological characteristics and its current treatments. Furthermore …
A monoclonal antibody to ADAM17 inhibits tumor growth by inhibiting EGFR and non–EGFR-Mediated pathways
J Rios-Doria, D Sabol, J Chesebrough, D Stewart… - Molecular Cancer …, 2015 - AACR
ADAM17 is the primary sheddase for HER pathway ligands. We report the discovery of a
potent and specific ADAM17 inhibitory antibody, MEDI3622, which induces tumor regression …
potent and specific ADAM17 inhibitory antibody, MEDI3622, which induces tumor regression …
Critical roles of EGFR family members in breast cancer and breast cancer stem cells: targets for therapy
LS Steelman, T Fitzgerald… - Current …, 2016 - ingentaconnect.com
The roles of the epidermal growth factor receptor (EGFR) signaling pathway in various
cancers including breast, bladder, brain, colorectal, esophageal, gastric, head and neck …
cancers including breast, bladder, brain, colorectal, esophageal, gastric, head and neck …
Gold Nanoparticles Enhance the Tumor Growth-Suppressing Effects of Cetuximab and Radiotherapy in Head and Neck Cancer In Vitro and In Vivo
T Sato, Y Kakei, T Hasegawa, M Kashin, S Teraoka… - Cancers, 2023 - mdpi.com
Simple Summary Head and neck squamous cell carcinoma (HNSCC) treatment includes
surgery, radiotherapy, and immunotherapy with the aim of eradicating cancer cells without …
surgery, radiotherapy, and immunotherapy with the aim of eradicating cancer cells without …
Interrogating tumor metabolism and tumor microenvironments using molecular positron emission tomography imaging. Theranostic approaches to improve …
O Jacobson, X Chen - Pharmacological Reviews, 2013 - ASPET
Positron emission tomography (PET) is a noninvasive molecular imaging technology that is
becoming increasingly important for the measurement of physiologic, biochemical, and …
becoming increasingly important for the measurement of physiologic, biochemical, and …
Toxicity of concurrent chemoradiotherapy with cetuximab for locoregionally advanced nasopharyngeal carcinoma
HX Feng, SP Guo, GR Li, WH Zhong, L Chen… - Medical oncology, 2014 - Springer
Overexpression of the epidermal growth factor receptor can be found in 80% of patients with
locoregionally advanced nasopharyngeal carcinoma (NPC) and is associated with shorter …
locoregionally advanced nasopharyngeal carcinoma (NPC) and is associated with shorter …
Meet the insidious players: Review of viral infections in head and neck cancer etiology with an update on clinical trials
Head and neck cancers (HNC) occur in the upper aerodigestive tract and are among the
most common cancers. The etiology of HNC is complex, involving many factors, including …
most common cancers. The etiology of HNC is complex, involving many factors, including …