The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which
not only arise during metabolic functions but also during the biotransformation of …

Hemochromatosis | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology Clinical …

Hepatocellular carcinoma (HCC) is a common malignancy and one of the leading causes of
cancer-related death. The biological process of HCC is complex, with multiple factors …

Haemochromatosis is characterised by elevated transferrin saturation (TSAT) and
progressive iron loading that mainly affects the liver. Early diagnosis and treatment by …

Abstract Background and Aims Insulin resistance and poor glycemic control are key drivers
of the development of NAFLD and have recently been shown to be associated with fibrosis …

Importance HFEgene–associated hereditary hemochromatosis type 1 (HH1) is
underdiagnosed, resulting in missed opportunities for preventing morbidity and mortality …

Thalassemia is a heterogeneous congenital hemoglobinopathy common in the
Mediterranean region, Middle East, Indian subcontinent, and Southeast Asia with increasing …

Objective The West China Hospital of Sichuan University collaborated with regional medical
consortia in Sichuan Province to launch a natural population cohort study (NPCS) to …

Abstract Background and Aims Hereditary hemochromatosis (HH) is associated with
increased risk of hepatocellular carcinoma (HCC). However, HCC risk factors within this …

Genomic information is poised to play an increasing role in clinical care, extending beyond
highly penetrant genetic conditions to less penetrant genotypes and common disorders. But …