[HTML][HTML] Signaling pathways in rheumatoid arthritis: implications for targeted therapy

Q Ding, W Hu, R Wang, Q Yang, M Zhu, M Li… - Signal transduction and …, 2023 - nature.com
Rheumatoid arthritis (RA) is an incurable systemic autoimmune disease. Disease
progression leads to joint deformity and associated loss of function, which significantly …

[HTML][HTML] The effects of epithelial–mesenchymal transitions in COPD induced by cigarette smoke: an update

X Su, W Wu, Z Zhu, X Lin, Y Zeng - Respiratory Research, 2022 - Springer
Cigarette smoke is a complex aerosol containing a large number of compounds with a
variety of toxicity and carcinogenicity. Long-term exposure to cigarette smoke significantly …

Periostin: an emerging activator of multiple signaling pathways

Z Wang, J An, D Zhu, H Chen, A Lin, J Kang… - Journal of Cell …, 2022 - Springer
Matricellular proteins are responsible for regulating the microenvironment, the behaviors of
surrounding cells, and the homeostasis of tissues. Periostin (POSTN), a non-structural …

Consequences of poly (ethylene oxide) and poloxamer P188 on transcription in healthy and stressed myoblasts

AA Crabtree, N Boehnke, FS Bates… - Proceedings of the …, 2023 - National Acad Sciences
Poly (ethylene oxide)(PEO) and poloxamers, a class of poly (ethylene oxide)-b-poly
(propylene oxide)-b-poly (ethylene oxide)(PEO-PPO-PEO) triblock copolymers, have many …

Apoptosis and eryptosis: similarities and differences

A Tkachenko - Apoptosis, 2024 - Springer
Eryptosis is a regulated cell death (RCD) of mature erythrocytes initially described as a
counterpart of apoptosis for enucleated cells. However, over the recent years, a growing …

[HTML][HTML] Mycobacterium tuberculosis PE_PGRS19 Induces Pyroptosis through a Non-Classical Caspase-11/GSDMD Pathway in Macrophages

J Qian, Y Hu, X Zhang, M Chi, S Xu, H Wang, X Zhang - Microorganisms, 2022 - mdpi.com
The PE/PPE protein family commonly exists in pathogenic species, such as Mycobacterium
tuberculosis, suggesting a role in virulence and its maintenance. However, the exact role of …

Suppression of the SLC7A11/glutathione axis causes ferroptosis and apoptosis and alters the mitogen-activated protein kinase pathway in nasopharyngeal carcinoma

HH Wang, SQ Fan, YT Zhan, SP Peng… - International Journal of …, 2024 - Elsevier
SLC7A11 is a unit of the glutamate cystine antiporter Xc− system. It functions to import
cystine for glutathione biosynthesis and maintains the redox balance in cells. Sorafenib …

A Selective Nano Cell Cycle Checkpoint Inhibitor Overcomes Leukemia Chemoresistance

J Sun, F Xia, S Zhang, B Zhang, Y Guan, X Hu, P Xue… - Small, 2023 - Wiley Online Library
Cell cycle checkpoint activation promotes DNA damage repair, which is highly associated
with the chemoresistance of various cancers including acute myeloid leukemia (AML) …

[HTML][HTML] FGF19 induces the cell cycle arrest at G2-phase in chondrocytes

H Chen, J Li, C Pi, D Guo, D Zhang, X Zhou… - Cell Death Discovery, 2023 - nature.com
Abstract Fibroblast growth factor 19 (FGF19) has appeared as a new possible avenue in the
treatment of skeletal metabolic disorders. However, the role of FGF19 on cell cycle …

Hemocyte proliferation is associated with blood color shade variation in the blood clam, Tegillarca granosa

Z Yang, X He, H Jin, D Su, Z Lin, H Liu, Y Bao - Aquaculture, 2023 - Elsevier
Blood color shade is closely related to the health status and nutritional value of the blood
clam, Tegillarca granosa. The blood color shade of T. granosa shows great variation and is …