Endocannabinoid signaling and epigenetics modifications in the neurobiology of stress-related disorders

AA Coelho, S Lima-Bastos, PH Gobira… - Neuronal …, 2023 - portlandpress.com
Stress exposure is associated with psychiatric conditions, such as depression, anxiety, and
post-traumatic stress disorder (PTSD). It is also a vulnerability factor to developing or …

Genomic factors and therapeutic approaches in HIV-associated neurocognitive disorders: a comprehensive review

A Borrajo, D Pérez-Rodríguez… - International Journal of …, 2023 - mdpi.com
HIV-associated neurocognitive disorders (HANDs) still persist despite improved life
expectancy, reduced viral loads, and decreased infection severity. The number of patients …

MiRNA differences related to treatment-resistant schizophrenia

D Pérez-Rodríguez, MA Penedo… - International Journal of …, 2023 - mdpi.com
Schizophrenia (SZ) is a serious mental disorder that is typically treated with antipsychotic
medication. Treatment-resistant schizophrenia (TRS) is the condition where symptoms …

HLGNN-MDA: heuristic learning based on graph neural networks for miRNA–disease association prediction

L Yu, B Ju, S Ren - International Journal of Molecular Sciences, 2022 - mdpi.com
Identifying disease-related miRNAs can improve the understanding of complex diseases.
However, experimentally finding the association between miRNAs and diseases is …

A novel variant in TAF1 affects gene expression and is associated with X-linked TAF1 intellectual disability syndrome

SE Hurst, E Liktor-Busa, A Moutal, S Parker… - Neuronal …, 2018 - portlandpress.com
We investigated the genome of a 5-year-old male who presented with global developmental
delay (motor, cognitive, and speech), hypotonia, possibly ataxia, and cerebellar hypoplasia …

MyBrain-Seq: A pipeline for MiRNA-seq data analysis in neuropsychiatric disorders

D Pérez-Rodríguez, RC Agís-Balboa… - Biomedicines, 2023 - mdpi.com
High-throughput sequencing of small RNA molecules such as microRNAs (miRNAs) has
become a widely used approach for studying gene expression and regulation. However …

The role of non-coding rnas in cerebellar development

M Rahimi-Balaei, M Ramirez, I Gupta… - development of the …, 2023 - Springer
Since the sequencing of the human and various mammalian genomes, it is clear that there
are far too few protein-coding genes to specify and coordinate the complex series of …

Predicting the Risk of Breast Cancer Recurrence and Metastasis based on miRNA Expression

Y Lv, Y Wang, Y Zhang, S Chen, Y Yao - Current Bioinformatics, 2024 - ingentaconnect.com
Background: Even after surgery, breast cancer patients still suffer from recurrence and
metastasis. Thus, it is critical to predict accurately the risk of recurrence and metastasis for …

Towards a Flexible and Portable Workflow for Analyzing MiRNA-Seq Neuropsychiatric Data: An Initial Replicability Assessment

D Pérez-Rodríguez, M Pérez-Rodríguez… - … Conference on Practical …, 2022 - Springer
In the last decade, miRNAs have attracted noticeable interest as potential biomarkers of
neuropsychiatric conditions. However, a standard methodology for miRNA-Seq analysis …

[PDF][PDF] Identificación de los mecanismos epigenéticos relacionados con los fenómenos de inmunosupresión en sepsis y su uso como biomarcadores de pronóstico

RO Verdegal, FV Pallardó, JL García - 2023 - roderic.uv.es
TesisROV _ FULL _ v3.2 Page 1 Identificación de los mecanismos epigenéticos relacionados
con los fenómenos de inmunosupresión en sepsis y su uso como biomarcadores de pronóstico …