In this state-of-the-art review, we highlight the major advances over the last 5 years in
neonatal acute kidney injury (AKI). Large multicenter studies reveal that neonatal AKI is …

Acute kidney injury (AKI) is a common occurrence in the neonatal intensive care unit (NICU).
In recent years, our knowledge of the incidence and impact of neonatal AKI on outcomes …

Results Twenty-one percent (449 of 2110) experienced early AKI. Early AKI was associated
with higher risk of death (adjusted odds ratio, 2.8; 95% confidence interval, 1.7 to 4.7) and …

Objective (s) To test if acute kidney injury (AKI) is preventable in patients in the neonatal
intensive care unit and if infants at high-risk of nephrotoxic medication-induced AKI can be …

Nephron number in humans varies up to 13‐fold, likely reflecting the impact of multiple
factors on kidney development, including inherited body size and ethnicity, as well as …

Low nephron number—resulting, for example, from prematurity or developmental anomalies—
is a risk factor for the development of hypertension, chronic kidney disease and kidney …

Children born at low birth weights (both due to prematurity and/or intrauterine growth
restriction) show increased risk of kidney dysfunction during adulthood. A better …

Acute kidney injury (AKI) is a common and life-threatening complication in critically ill
neonates. Gestational risk factors for AKI include premature birth, intrauterine growth …

Importance Acute kidney injury (AKI) occurs commonly in preterm neonates and is
associated with increased morbidity and mortality. Objectives To examine the association …

Importance The incidence and associated outcomes of recurrent acute kidney injury (rAKI) in
neonates remain largely unknown. Objective To determine the incidence, risk factors, and …