A review: Gelatine as a bioadhesive material for medical and pharmaceutical applications

A Ahmady, NHA Samah - International Journal of Pharmaceutics, 2021 - Elsevier
Bioadhesive polymers offer versatility to medical and pharmaceutical inventions. The
incorporation of such materials to conventional dosage forms or medical devices may confer …

Novel and revisited approaches in nanoparticle systems for buccal drug delivery

AS Macedo, PM Castro, L Roque, NG Thomé… - Journal of Controlled …, 2020 - Elsevier
The buccal route is considered patient friendly due to its non-invasive nature and ease of
administration. Such delivery route has been used as an alternative for the delivery of drugs …

[HTML][HTML] Matrikines as mediators of tissue remodelling

N Jariwala, M Ozols, M Bell, E Bradley… - Advanced drug delivery …, 2022 - Elsevier
Extracellular matrix (ECM) proteins confer biomechanical properties, maintain cell
phenotype and mediate tissue repair (via release of sequestered cytokines and proteases) …

Strategies and industrial perspectives to improve oral absorption of biological macromolecules

C Liu, Y Kou, X Zhang, H Cheng, X Chen… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Therapeutic proteins have become a highly attractive drug of choice due to
minimal toxicity, high activity and exquisite specificity. Oral delivery of protein drugs is a very …

[HTML][HTML] Bioadhesive nanoparticles for local drug delivery

L Yu, Z Luo, T Chen, Y Ouyang, L Xiao, S Liang… - International Journal of …, 2022 - mdpi.com
Local drug delivery is an effective strategy for achieving direct and instant therapeutic
effects. Current clinical treatments have fallen short and are limited by traditional …

In vivo challenges of anti-diabetic peptide therapeutics: Gastrointestinal stability, toxicity and allergenicity

PG Yap, CY Gan - Trends in Food Science & Technology, 2020 - Elsevier
Background A plethora of research has explored the potential of bioactive peptide as a new
class of drug therapeutics, yet only a minute amount has successfully translated into clinical …

[HTML][HTML] Formulation challenges and strategies to develop pediatric dosage forms

WA Malkawi, E AlRafayah, M AlHazabreh, S AbuLaila… - Children, 2022 - mdpi.com
The development of pediatric-specific dose forms is particularly difficult due to a variety of
factors relating to pediatric population differences from adult populations. The buccal …

[HTML][HTML] A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates

JSR Costa, K de Oliveira Cruvinel… - Journal of advanced …, 2019 - Elsevier
A great number of patients have difficulty swallowing or needle fear. Therefore, buccal and
orodispersible dosage forms (ODFs) represent an important strategy to enhance patient …

[HTML][HTML] Pharmacokinetic aspects of nanoparticle-in-matrix drug delivery systems for oral/buccal delivery

RC Feitosa, DC Geraldes… - Frontiers in …, 2019 - frontiersin.org
Oral route maintains its predominance among the ones used for drug delivery, especially
when medicines are self-administered. If the dosage form is solid, therapy gains in dose …

The effect of topical chamomile in the prevention of chemotherapy‐induced oral mucositis: A randomized clinical trial

MA Elhadad, E El‐Negoumy, MR Taalab… - Oral …, 2022 - Wiley Online Library
Objective To clinically assess the effectiveness of topical chamomile oral gel in the
prevention of chemotherapy‐induced oral mucositis. Material and methods A parallel single …