Insights into the effect of glucose on the binding between human serum albumin and the nonsteroidal anti-inflammatory drug nimesulide

MAG Soares, PA de Aquino, T Costa, C Serpa… - International Journal of …, 2024 - Elsevier
Glucose interacts with human serum albumin (HSA, the main protein responsible for the
biodistribution of drugs in the bloodstream) and consequently affects the binding capacity of …

The Study of Molecules and Processes in Solution: An Overview of Questions, Approaches and Applications

N Tshilande, L Mammino, MK Bilonda - Computation, 2024 - mdpi.com
Many industrial processes, several natural processes involving non-living matter, and all the
processes occurring within living organisms take place in solution. This means that the …

Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations

U Tutar, C Çelik, E Üstün, N Özdemir, N Şahin… - Inorganics, 2023 - mdpi.com
Five silver (I) complexes, namely chloro [1-methallyl-3-benzyl) benzimidazol-2-ylidene]
silver (6), chloro [1-methallyl-3-(2, 3, 5, 6-tetramethylbenzyl) benzimidazol-2-ylidene] silver …

2-Butoxytetrahydrofuran, Isolated from Holothuria scabra, Attenuates Aggregative and Oxidative Properties of α-Synuclein and Alleviates Its Toxicity in a Transgenic …

S Promtang, T Sanguanphun, P Chalorak… - ACS Chemical …, 2024 - ACS Publications
Aggregative α-synuclein and incurring oxidative stress are pivotal cascading events, leading
to dopaminergic (DAergic) neuronal loss and contributing to clinical manifestations of …

Computational exploration of Picrasma quassioides compounds as CviR-mediated quorum sensing inhibitors against Chromobacterium violaceum

PD Revanasiddappa, G HG, C KP… - Frontiers in …, 2024 - frontiersin.org
Chromobacterium violaceum an opportunistic human pathogenic bacterium, exhibits
resistance to conventional antibiotics by exploiting its quorum sensing mechanism to …

Falcaria vulgaris extract: A mixture of quorum sensing inhibitors for controlling Pectobacterium carotovorum subsp. carotovorum

MR Alymanesh, A Solhjoo, E Pishgar, M Akhlaghi - Food Microbiology, 2024 - Elsevier
A promising strategy to control bacterial diseases involves using Quorum Sensing Inhibitor
(QSI) compounds. This study aimed to evaluate the potential of Falcaria vulgaris plant …

Interaction of Norsecurinine-Type Oligomeric Alkaloids with α-Tubulin: A Molecular Docking Study

G Vergoten, C Bailly - Plants, 2024 - mdpi.com
The medicinal plant Securinega virosa (Roxb ex. Willd) Baill., also known as Flueggea
virosa (Roxb. ex Willd.) Royle, is commonly used in traditional medicine in Africa and Asia …

The Leptospermum scoparium (Mānuka)-Specific Nectar and Honey Compound 3,6,7-Trimethyllumazine (LepteridineTM) That Inhibits Matrix Metalloproteinase 9 …

B Lin, S Nair, DMJ Fellner, NA Nasef, H Singh… - Foods, 2023 - mdpi.com
3, 6, 7-trimethyllumazine (Lepteridine™) is a newly discovered natural pteridine derivative
unique to Mānuka (Leptospermum scoparium) nectar and honey, with no previously …

Exploring the Staphylococcus aureus Gyrase Complex and Human Topoisomerase: Potential Target for Molecular Docking and Biological Studies with Substituted …

R Tomar, P Sarkar, V Srivastava, P Gupta, S Malik… - ACS …, 2023 - ACS Publications
This paper targets the nuclease activity of polymeric chemical compounds toward bacterial
genomic DNA and also elucidates their probable drug-like properties against the enzymes …

Extraction and Characterizations of Viral Protein Particles: A Methodological Study

M Manoswini, M Mohanty, AG Majumdar, BR Sahu… - BioNanoScience, 2024 - Springer
Phage (viral) tailspike proteins (TSP) are used in many translation applications such as in
pathogenic bacteria detection and therapeutics. Especially, bacterial virus (or …