Self‐assembled peptide‐based nanomaterials for biomedical imaging and therapy

GB Qi, YJ Gao, L Wang, H Wang - Advanced materials, 2018 - Wiley Online Library
Peptide‐based materials are one of the most important biomaterials, with diverse structures
and functionalities. Over the past few decades, a self‐assembly strategy is introduced to …

A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly

SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Intelligent biomaterialomics: molecular design, manufacturing, and biomedical applications

Y Yi, HW An, H Wang - Advanced Materials, 2024 - Wiley Online Library
Materialomics integrates experiment, theory, and computation in a high‐throughput manner,
and has changed the paradigm for the research and development of new functional …

Endogenous reactive oxygen species-triggered morphology transformation for enhanced cooperative interaction with mitochondria

DB Cheng, XH Zhang, YJ Gao, L Ji, D Hou… - Journal of the …, 2019 - ACS Publications
The morphology controlled molecular assemblies play vital roles in biological systems. Here
we present endogenous reactive oxygen species (ROS)-triggered morphology …

Polymeric nanoparticles promote macrophage reversal from M2 to M1 phenotypes in the tumor microenvironment

Y Wang, YX Lin, SL Qiao, HW An, Y Ma, ZY Qiao… - Biomaterials, 2017 - Elsevier
Immunotherapy has shown promising treatment effects for a variety of cancers. However, the
immune treatment efficiency for solid tumors is limited owing to insufficient infiltration of …

Microenvironment‐induced in situ self‐assembly of polymer–peptide conjugates that attack solid tumors deeply

Y Cong, L Ji, YJ Gao, FH Liu, DB Cheng… - Angewandte …, 2019 - Wiley Online Library
In cancer treatment, the unsatisfactory solid‐tumor penetration of nanomaterials limits their
therapeutic efficacy. We employed an in vivo self‐assembly strategy and designed polymer …

A self-destructive nanosweeper that captures and clears amyloid β-peptides

Q Luo, YX Lin, PP Yang, Y Wang, GB Qi… - Nature …, 2018 - nature.com
Cerebral amyloid β-peptide (Aβ) accumulation resulting from an imbalance between Aβ
production and clearance is one of the most important causes in the formation of Alzheimer's …

An “On‐Site Transformation” strategy for treatment of bacterial infection

GB Qi, D Zhang, FH Liu, ZY Qiao… - Advanced Materials, 2017 - Wiley Online Library
To date, numerous nanosystems have been developed as antibiotic replacements for
bacterial infection treatment. However, these advanced systems are limited owing to their …

Ring-Opening Polymerization of N-Carboxyanhydride-Induced Self-Assembly for Fabricating Biodegradable Polymer Vesicles

J Jiang, X Zhang, Z Fan, J Du - ACS Macro Letters, 2019 - ACS Publications
Polymerization-induced self-assembly (PISA) is regarded as one of the most important
strategies in macromolecular nanotechnology, as it can create a wide range of nanoparticles …

Self-motivated supramolecular combination chemotherapy for overcoming drug resistance based on acid-activated competition of host–guest interactions

H Wang, H Wu, Y Yi, KF Xue, JF Xu, H Wang… - CCS …, 2021 - chinesechemsoc.org
In this work, we propose a nanoparticle-based strategy of self-motivated supramolecular
combination chemotherapy that carries drugs stably and releases them actively in the acidic …