Mitochondria contain connexins, a family of proteins that is known to form gap junction
channels. Connexins are synthesized in the endoplasmic reticulum and oligomerized in the …

Exogenous RNA poses a continuous threat to genome stability and integrity across various
organisms. Accumulating evidence reveals complex mechanisms underlying the cellular …

The kidney is an energy-consuming organ, and cellular metabolism plays an indispensable
role in kidney-related diseases. Caveolin-1 (Cav-1), a multifunctional membrane protein, is …

The overexpression of hepatic growth factor (HGF) is one of the important reasons for the
development of gefitinib resistance in EGFR-sensitive mutant lung adenocarcinoma cells …

Connexins (Cxs) are ubiquitous transmembrane proteins that possess both channel function
(eg, formations of gap junction and hemichannel) and non-channel properties (eg, gene …

Anatomical and electrophysiological evidence that gap junctions and electrical coupling
occur between neurons was initially confined to invertebrates and nonmammals and was …

Abstract Ca2+/calmodulin-dependent protein kinase II (CaMKII) binding and
phosphorylation of mammalian connexin-36 (Cx36) potentiate electrical coupling. To …

Proteins fated to be internalized by clathrin-mediated endocytosis require an endocytic motif,
where AP-2 or another adaptor protein can bind and recruit clathrin. Tyrosine and di-leucine …

Background Pemphigus vulgaris (PV) is a potentially fatal autoimmune bullous disease
primarily caused by acantholysis of keratinocytes attributed to pathogenic desmoglein‐3 …

The interaction between terbium-doped arginine functionalized hydroxyapatite
nanoparticles (Arg@ HAP Tb NPs) and cells, and the hindered endocytosis mechanisms of …