Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

A review of NIR dyes in cancer targeting and imaging

S Luo, E Zhang, Y Su, T Cheng, C Shi - Biomaterials, 2011 - Elsevier
The development of multifunctional agents for simultaneous tumor targeting and near
infrared (NIR) fluorescence imaging is expected to have significant impact on future …

Method to diversify cyanine chromophore functionality enables improved biomolecule tracking and intracellular imaging

SM Usama, SC Marker, DH Li… - Journal of the …, 2023 - ACS Publications
Heptamethine indocyanines are invaluable probes for near-infrared (NIR) imaging. Despite
broad use, there are only a few synthetic methods to assemble these molecules, and each …

Review of long-wavelength optical and NIR imaging materials: contrast agents, fluorophores, and multifunctional nano carriers

VJ Pansare, S Hejazi, WJ Faenza… - Chemistry of …, 2012 - ACS Publications
The importance of long wavelength and near-infrared (NIR) imaging has dramatically
increased due to the desire to perform whole animal and deep tissue imaging. The adoption …

Image-guided surgery using invisible near-infrared light: fundamentals of clinical translation

S Gioux, HS Choi, JV Frangioni - Molecular imaging, 2010 - journals.sagepub.com
The field of biomedical optics has matured rapidly over the last decade and is poised to
make a significant impact on patient care. In particular, wide-field (typically> 5 cm), planar …

Sterically shielded heptamethine cyanine dyes for bioconjugation and high performance near‐infrared fluorescence imaging

DH Li, CL Schreiber, BD Smith - Angewandte Chemie, 2020 - Wiley Online Library
The near‐infrared window of fluorescent heptamethine cyanine dyes greatly facilitates
biological imaging because there is deep penetration of the light and negligible background …

Synthesis and in vivo fate of zwitterionic near‐infrared fluorophores

HS Choi, K Nasr, S Alyabyev, D Feith… - Angewandte Chemie …, 2011 - Wiley Online Library
A longstanding problem in the field of image-guided surgery is the development of ideal
near-infrared (NIR) fluorophores. The heptamethine NIR fluorophore indocyanine green …

Harnessing cyanine reactivity for optical imaging and drug delivery

AP Gorka, RR Nani… - Accounts of chemical …, 2018 - ACS Publications
Conspectus Optical approaches that visualize and manipulate biological processes have
transformed modern biomedical research. An enduring challenge is to translate these …

Explorations into the Effect of meso‐Substituents in Tricarbocyanine Dyes: A Path to Diverse Biomolecular Probes and Materials

RM Exner, F Cortezon‐Tamarit… - Angewandte Chemie …, 2021 - Wiley Online Library
Polymethine cyanine dyes have been widely recognized as promising chemical tools for a
range of life science and biomedical applications, such as fluorescent staining of DNA and …

Development of photostable near-infrared cyanine dyes

A Samanta, M Vendrell, R Das, YT Chang - Chemical communications, 2010 - pubs.rsc.org
With the emerging interest in optical in vivo imaging, there is an increasing demand of
photostable near-infrared (NIR) dyes. Herein we report the rational design of an amine …