National human embryo and embryoid research policies: a survey of 22 top research-intensive countries

KRW Matthews, D Moralí - Regenerative medicine, 2020 - Taylor & Francis
Research using human embryos and embryoids has expanded in recent years due to
technological advances. Surveying laws and guidelines among the top research and …

Ethical, legal, regulatory, and policy issues concerning embryoids: a systematic review of the literature

AS Iltis, G Koster, E Reeves, KRW Matthews - Stem Cell Research & …, 2023 - Springer
Recent advances in methods to culture pluripotent stem cells to model human development
have resulted in entities that increasingly have recapitulated advanced stages of early …

Potential ethical problems with human cerebral organoids: consciousness and moral status of future brains in a dish

A Lavazza - Brain Research, 2021 - Elsevier
Human cerebral organoids (HCOs) are an in vitro model of early neural development, aimed
at modelling and understanding brain development and neurological disorders. In just a few …

The ethics of human-embryoids model: a call for consistency

P Nicolas, F Etoc, AH Brivanlou - Journal of Molecular Medicine, 2021 - Springer
In this article, we discuss the ethics of human embryoids, ie, embryo-like structures made
from pluripotent stem cells for modeling natural embryos. We argue that defining our social …

CRISPR in context: towards a socially responsible debate on embryo editing

M Morrison, S de Saille - Palgrave Communications, 2019 - nature.com
Following the birth in 2018 of two babies from embryos altered using CRISPR-Cas9, human
germline gene editing (GGE) moved from abstract concern to reality. He Jiankui, the scientist …

'Ceci n'est pas un embryon?'The ethics of human embryo model research

N de Graeff, L De Proost, M Munsie - Nature methods, 2023 - nature.com
‘Ceci n’est pas un embryon?’ The ethics of human embryo model research | Nature Methods
Skip to main content Thank you for visiting nature.com. You are using a browser version with …

Human cerebral organoids and consciousness: a double-edged sword

A Lavazza - Monash bioethics review, 2020 - Springer
Human cerebral organoids (HCOs) are three-dimensional in vitro cell cultures that mimic the
developmental process and organization of the developing human brain. In just a few years …

[HTML][HTML] Adapting the 14-day rule for embryo research to encompass evolving technologies

K Williams, MH Johnson - Reproductive Biomedicine & Society Online, 2020 - Elsevier
We consider the scientific evidence that research on in-vitro development of embryos
beyond 14 days is necessary. We then examine potential new developments in the use of …

Revisiting selected ethical aspects of current clinical in vitro fertilization (IVF) practice

A von Schondorf-Gleicher, L Mochizuki… - Journal of assisted …, 2022 - Springer
Ethical considerations are central to all medicine though, likely, nowhere more essential
than in the practice of reproductive endocrinology and infertility. Through in vitro fertilization …

Are we ready for the revision of the 14-day rule? Implications from Chinese legislations guiding human embryo and embryoid research

Y Xue, L Shang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The ISSCR recently released new guidelines that relaxed the 14-day rule taking away the
tough barrier, and this has rekindled relevant ethical controversies and posed a fresh set of …