Nanogels: Synthesis, properties, and recent biomedical applications

QY Duan, YX Zhu, HR Jia, SH Wang, FG Wu - Progress in Materials …, 2023 - Elsevier
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …

Harnessing polymer-derived drug delivery systems for combating inflammatory bowel disease

Y Pu, X Fan, Z Zhang, Z Guo, Q Pan, W Gao… - Journal of Controlled …, 2023 - Elsevier
The inflammatory bowel disease (IBD) is incurable, chronic, recrudescent disorders in the
inflamed intestines. Current clinic treatments are challenged by systemic exposure-induced …

[HTML][HTML] Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair

H Sun, J Xu, Y Wang, S Shen, X Xu, L Zhang, Q Jiang - Bioactive materials, 2023 - Elsevier
Large bone defects resulting from fractures and disease are a major clinical challenge,
being often unable to heal spontaneously by the body's repair mechanisms. Lines of …

Selective degradation of organic micropollutants by activation of peroxymonosulfate by Se@ NC: Role of Se doping and nonradical pathway mechanism

Y Chai, H Dai, P Zhan, Z Liu, Z Huang, C Tan… - Journal of Hazardous …, 2023 - Elsevier
In this study, Se@ NC-x decorated with Se was successfully prepared via two-step
calcination with zeolitic imidazole framework (ZIF) as a precursor. Mechanistic studies show …

Probiotic‐inspired nanomedicine restores intestinal homeostasis in colitis by regulating redox balance, immune responses, and the Gut Microbiome

J Xu, J Xu, T Shi, Y Zhang, F Chen, C Yang… - Advanced …, 2023 - Wiley Online Library
Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …

An orally-administered nanotherapeutics with carbon monoxide supplying for inflammatory bowel disease therapy by scavenging oxidative stress and restoring gut …

X Zhang, Z Yuan, J Wu, Y He, G Lu, D Zhang, Y Zhao… - ACS …, 2023 - ACS Publications
Traditional drug-based treatments for inflammatory bowel disease (IBD) have significant
limitations due to their potential off-target systemic side-effects. Currently, there is a lack of …

Glycopeptide‐Based Multifunctional Hydrogels Promote Diabetic Wound Healing through pH Regulation of Microenvironment

H Xia, Z Dong, Q Tang, R Ding, Y Bai… - Advanced functional …, 2023 - Wiley Online Library
Excessive inflammation, bacterial infection, and blocked angiogenesis make diabetic wound
healing challenging. Multifunctional wound dressings have several advantages in diabetic …

Oral nanomedicine: challenges and opportunities

B Deng, S Liu, Y Wang, B Ali, N Kong, T Xie… - Advanced …, 2024 - Wiley Online Library
Compared to injection administration, oral administration is free of discomfort, wound
infection, and complications and has a higher compliance rate for patients with diverse …

An engineered butyrate-derived polymer nanoplatform as a mucosa-healing enhancer potentiates the therapeutic effect of magnolol in inflammatory bowel disease

X Fan, Z Zhang, W Gao, Q Pan, K Luo, B He, Y Pu - ACS nano, 2023 - ACS Publications
Colonic epithelial damage and dysregulated immune response are crucial factors in the
progression and exacerbation of inflammatory bowel disease (IBD). Nanoenabled targeted …

Microenvironment-responsive nanocarriers for targeted bone disease therapy

M Li, B Yu, S Wang, F Zhou, J Cui, J Su - Nano Today, 2023 - Elsevier
Nanomedicines with controlled drug release have received increasing attention as an
advanced therapeutic strategy for bone diseases. To traverse biological barriers towards …