[HTML][HTML] The evolution of SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …
[HTML][HTML] Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination
R Pecori, S Di Giorgio, J Paulo Lorenzo… - Nature Reviews …, 2022 - nature.com
The AID/APOBEC polynucleotide cytidine deaminases have historically been classified as
either DNA mutators or RNA editors based on their first identified nucleic acid substrate …
either DNA mutators or RNA editors based on their first identified nucleic acid substrate …
[HTML][HTML] Spread of a SARS-CoV-2 variant through Europe in the summer of 2020
Following its emergence in late 2019, the spread of SARS-CoV-2, has been tracked by
phylogenetic analysis of viral genome sequences in unprecedented detail,–. Although the …
phylogenetic analysis of viral genome sequences in unprecedented detail,–. Although the …
COVID-19 Vaccine: A comprehensive status report
The current COVID-19 pandemic has urged the scientific community internationally to find
answers in terms of therapeutics and vaccines to control SARS-CoV-2. Published …
answers in terms of therapeutics and vaccines to control SARS-CoV-2. Published …
[HTML][HTML] Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants
Neutralizing antibodies elicited by prior infection or vaccination are likely to be key for future
protection of individuals and populations against SARS-CoV-2. Moreover, passively …
protection of individuals and populations against SARS-CoV-2. Moreover, passively …
[HTML][HTML] Emerging SARS-CoV-2 variants of concern and potential intervention approaches
J Khateeb, Y Li, H Zhang - Critical Care, 2021 - Springer
The major variant of concerns (VOCs) have shared mutations in severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) spike proteins, mostly on the S1 unit and resulted in …
syndrome coronavirus 2 (SARS-CoV-2) spike proteins, mostly on the S1 unit and resulted in …
[HTML][HTML] The impact of mutations in SARS-CoV-2 spike on viral infectivity and antigenicity
Q Li, J Wu, J Nie, L Zhang, H Hao, S Liu, C Zhao… - Cell, 2020 - cell.com
The spike protein of SARS-CoV-2 has been undergoing mutations and is highly
glycosylated. It is critically important to investigate the biological significance of these …
glycosylated. It is critically important to investigate the biological significance of these …
[HTML][HTML] On the origin and evolution of SARS-CoV-2
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
ongoing global outbreak of a coronavirus disease (herein referred to as COVID-19). Other …
ongoing global outbreak of a coronavirus disease (herein referred to as COVID-19). Other …
CoroDet: A deep learning based classification for COVID-19 detection using chest X-ray images
Abstract Background and Objective The Coronavirus 2019, or shortly COVID-19, is a viral
disease that causes serious pneumonia and impacts our different body parts from mild to …
disease that causes serious pneumonia and impacts our different body parts from mild to …
[HTML][HTML] Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
The receptor binding domain (RBD) of the SARS-CoV-2 spike glycoprotein mediates viral
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …
attachment to ACE2 receptor and is a major determinant of host range and a dominant target …