Abstract Alzheimer's disease (AD), as the fourth leading cause of death among the elderly
worldwide, has brought enormous challenge to the society. Due to its extremely complex …

In recent years, a great deal of attention has been paid to natural compounds due to their
many biological effects. Polyphenols are a class of plant derivatives that have been widely …

The potassium channel Kv1. 3 is highly expressed in the mitochondria of various cancerous
cells. Here we show that direct inhibition of Kv1. 3 using two mitochondria-targeted inhibitors …

Gallic acid (3, 4, 5-trihydroxybenzoic acid, GA) is a plant secondary metabolite, which shows
antioxidant activity and is commonly found in many plant-based foods and beverages …

Prodrugs of resveratrol are under development. Among the long‐term goals, still largely
elusive, are (1) modulating physical properties (eg, water‐soluble derivatives bearing …

Enzymatic esterification of resveratrol is crucial for its potential application in lipophilic foods
and drugs. However, the poor activity of the free enzyme hinders the reaction. In this work …

Pancreatic ductal adenocarcinoma (PDAC) represents the most common form of pancreatic
cancer with rising incidence in developing countries. Unfortunately, the overall 5-year …

Curcumin is a polyphenol compound that alleviates several neuroinflammation-related
diseases including Alzheimer's disease, Parkinson's disease, multiple sclerosis, epilepsy …

Resveratrol (RES) suffers from poor water solubility and extensive metabolism, which lead to
low bioavailability. A phospholipid complex (PC) containing RES and a UDP …

The biomedical effects of the natural phenol pterostilbene are of great interest but its
bioavailability is negatively affected by the phenolic group in position 4′ which is an ideal …