Multi‐Chromatic pH‐Activatable 19F‐MRI Nanoprobes with Binary ON/OFF pH Transitions and Chemical‐Shift Barcodes
X Huang, G Huang, S Zhang… - Angewandte Chemie …, 2013 - Wiley Online Library
Magnetic resonance imaging (MRI) is a powerful noninvasive imaging technique that has
greatly impacted basic biological research as well clinical diagnosis of cancer and other …
greatly impacted basic biological research as well clinical diagnosis of cancer and other …
Structure–redox–relaxivity relationships for redox responsive manganese-based magnetic resonance imaging probes
EM Gale, S Mukherjee, C Liu, GS Loving… - Inorganic …, 2014 - ACS Publications
A library of 10 Mn-containing complexes capable of switching reversibly between the Mn (II)
and Mn (III) oxidation states was prepared and evaluated for potential usage as MRI …
and Mn (III) oxidation states was prepared and evaluated for potential usage as MRI …
[HTML][HTML] Spatiotemporal pH heterogeneity as a promoter of cancer progression and therapeutic resistance
DE Korenchan, RR Flavell - Cancers, 2019 - mdpi.com
Dysregulation of pH in solid tumors is a hallmark of cancer. In recent years, the role of
altered pH heterogeneity in space, between benign and aggressive tissues, between …
altered pH heterogeneity in space, between benign and aggressive tissues, between …
Magnetic resonance spectroscopy in metabolic and molecular imaging and diagnosis of cancer
Since its discovery in the 1940s, magnetic resonance spectroscopy (MRS) has developed
into a major technique used by chemists to elucidate molecular structures. The underlying …
into a major technique used by chemists to elucidate molecular structures. The underlying …
Potentiometric and relaxometric properties of a gadolinium-based MRI contrast agent for sensing tissue pH
The pH-sensitive contrast agent, GdDOTA-4AmP (Gd 1) has been successfully used to map
tissue pH by MRI. Further studies now demonstrate that two distinct chemical forms of the …
tissue pH by MRI. Further studies now demonstrate that two distinct chemical forms of the …
A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol
Purpose To extend the pH detection range of iopamidol‐based ratiometric chemical
exchange saturation transfer (CEST) MRI at sub‐high magnetic field and establish …
exchange saturation transfer (CEST) MRI at sub‐high magnetic field and establish …
Gd (iii) chelates for MRI contrast agents: from high relaxivity to “smart”, from blood pool to blood–brain barrier permeable
Paramagnetic Gd (III) chelate contrast agents have been extensively used to enhance the
signal of MRI scans for the last three decades. The use of Gd (III) chelate contrast agents is …
signal of MRI scans for the last three decades. The use of Gd (III) chelate contrast agents is …
Imaging in vivo extracellular pH with a single paramagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent
G Liu, Y Li, VR Sheth, MD Pagel - Molecular imaging, 2012 - journals.sagepub.com
The measurement of extracellular pH (pHe) has potential utility for cancer diagnoses and for
assessing the therapeutic effects of pH-dependent therapies. A single magnetic resonance …
assessing the therapeutic effects of pH-dependent therapies. A single magnetic resonance …
Employing paramagnetic shift for responsive MRI probes
Paramagnetic metal ions with anisotropic magnetic susceptibilities can shift the proton NMR
signals of chelating ligands beyond the diamagnetic range of endogenous proton …
signals of chelating ligands beyond the diamagnetic range of endogenous proton …
Detection of tissue pH with quantitative chemical exchange saturation transfer magnetic resonance imaging
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
emerged as a novel means for sensitive detection of dilute labile protons and chemical …
emerged as a novel means for sensitive detection of dilute labile protons and chemical …