Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

Cancer therapy resistance is the main cause of cancer treatment failure. The mechanism of
therapy resistance is a hot topic in epigenetics. As one of the most common RNA …

Background & Aims Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-
related deaths worldwide, but there is a deficiency of early diagnosis biomarkers and …

RNA modification has recently become a significant process of gene regulation, and the
methyltransferase-like (METTL) family of proteins plays a critical role in RNA modification …

Abstract N6-methyladenosine (m6A) methylation is the most universal internal modification
in eukaryotic mRNA. With elaborate functions executed by m6A writers, erasers, and …

Background The response rate to immunotherapy in patients with bladder cancer (BCa)
remains relatively low. Considering the stable existence and important functions in tumour …

RNA methylation is a critical mechanism for regulating the transcription and translation of
specific sequences or for eliminating unnecessary sequences during RNA maturation …

The majority of human mRNAs generate alternative 3′ untranslated regions (UTRs)
through various processes, including RNA modifications such as RNA editing, m 6 A …

The tumor microenvironment (TME) is a heterogeneous ecosystem containing cancer cells,
immune cells, stromal cells, cytokines, and chemokines which together govern tumor …

The treatment options for advanced papillary thyroid cancer (PTC) and anaplastic thyroid
cancer (ATC) refractory to standard therapies are limited. Although anti-PD-1 therapy has a …