Ciliates are a highly divergent group of unicellular eukaryotes with separate somatic and
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …

The formation of resting cysts commonly found in unicellular eukaryotes is a complex and
highly regulated survival strategy against environmental stress that involves drastic …

The unicellular ciliate Paramecium contains a large vegetative macronucleus with several
unusual characteristics, including an extremely high coding density and high polyploidy. As …

Most eukaryotes have one nucleus and nuclear genome per cell. Ciliates have instead
evolved distinct nuclei that coexist in each cell: a silent germline vs. transcriptionally active …

Methylcytosine (5mC) and DNA methyltransferases (DNMTs) are broadly conserved in
eukaryotes but are also frequently lost during evolution. The mammalian SNF2 family …

Trichomonas vaginalis is a common sexually transmitted parasite that colonizes the human
urogenital tract causing infections that range from asymptomatic to highly inflammatory …

Transposable elements and related DNA sequences, such as remnants of retrotransposons,
constitute a substantial portion of eukaryotic genomes. The widespread presence of these …

DNA methylation is a common, but not universal, epigenetic modification that plays an
important role in multiple cellular processes. While definitely settled for numerous plant …

G. intestinalis is an intestinal protozoan parasite that causes 180 million symptomatic
diarrheacases (giardiasis) and more than 0.5 billion asymptomatic infections per year …

Trichomonas vaginalis is a common sexually transmitted parasite that colonizes the human
urogenital tract causing infections that range from asymptomatic to highly inflammatory …