Evaluation of repeated or acute treatment with cannabidiol (CBD), cannabidiolic acid (CBDA) or CBDA methyl ester (HU-580) on nausea and/or vomiting in rats and …

EM Rock, MT Sullivan, SA Collins, H Goodman… - …, 2020 - Springer
Rationale When acutely administered intraperitoneally, the non-psychoactive cannabinoid
cannabidiol (CBD), its acidic precursor cannabidiolic acid (CBDA) and a stable methyl ester …

Is cannabidiolic acid an overlooked natural antioxidant? Insights from quantum chemistry calculations

H Boulebd - New Journal of Chemistry, 2022 - pubs.rsc.org
Cannabidiolic acid (CBDA) is one of the most abundant phytocannabinoids found in
cannabis. This compound has demonstrated interesting biological activities, including anti …

Antinociceptive effects of minor cannabinoids, terpenes and flavonoids in Cannabis

CEB Rodriguez, L Ouyang… - Behavioural …, 2022 - journals.lww.com
Cannabis has been used for centuries for its medicinal properties. Given the dangerous and
unpleasant side effects of existing analgesics, the chemical constituents of Cannabis have …

Thrips resistance screening is coming of age: leaf position and ontogeny are important determinants of leaf-based resistance in pepper

IGS Visschers, JL Peters… - Frontiers in Plant …, 2019 - frontiersin.org
Capsicum is a genus containing important crop species, many of which severely suffer from
thrips infestation. Thrips feeding damages leaves and fruits, and often results in virus …

Rapid isolation of acidic cannabinoids from Cannabis sativa L. using pH-zone-refining centrifugal partition chromatography

JR Popp, EA Petrakis, A Angelis, M Halabalaki… - … of Chromatography A, 2019 - Elsevier
This work introduces an effective methodology for the isolation of acidic cannabinoids from
fiber-type Cannabis sativa L. Supercritical fluid extraction (SFE) was initially employed to …

Cannabidiol but not cannabidiolic acid reduces behavioural sensitisation to methamphetamine in rats, at pharmacologically effective doses

LS Umpierrez, PA Costa, EA Michelutti, SJ Baracz… - …, 2022 - Springer
Rationale Cannabidiol (CBD) and cannabidiolic acid (CBDA) are non-psychoactive
components of the cannabis plant. CBD has been well characterised to have anxiolytic and …

Using cannabis to treat cancer-related pain

T Byars, E Theisen, DL Bolton - Seminars in oncology nursing, 2019 - Elsevier
Objective To describe which cannabinoids and terpenes are effective for treating pain. Data
Sources Peer-reviewed articles, book chapters. Conclusion Cannabis and cannabinoid …

The pharmacology and therapeutic potential of plant cannabinoids

MG Cascio, RG Pertwee, P Marini - Cannabis sativa L.-botany and …, 2017 - Springer
The plant Cannabis sativa has been widely used by humans over many centuries as a
source of fibre, for medicinal purposes, for religious ceremonies and as a recreational drug …

Biological activity of Cannabis compounds: a modern approach to the therapy of multiple diseases

M Helcman, K Šmejkal - Phytochemistry Reviews, 2022 - Springer
Cannabis spp. are some of the most controversial medicinal plants in the world. They
contain great amounts of biologically active secondary metabolites, including the typical …

Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Δ9‐tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism …

EM Rock, MA Sticht, M Duncan, C Stott… - British journal of …, 2013 - Wiley Online Library
Background and Purpose The cannabinoid 1 (CB1) receptor inverse agonists/antagonists,
rimonabant (SR 141716, SR) and AM251, produce nausea and potentiate toxin‐induced …