Rett syndrome (RTT) is a rare neurologic disorder, characterized by severe behavioural and
physiological symptoms. RTT is caused by mutations in the MECP2 gene in about 95% of …

Rationale The effectiveness of cannabidiolic acid (CBDA) was compared with other potential
treatments for anticipatory nausea (AN), using a rat model of contextually elicited …

Using the rat conditioned gaping model of nausea, the interoceptive insular cortex (IIC) has
been identified as a critical site for the regulation of lithium chloride (LiCl)-induced nausea …

After a long period defined by prohibition of hemp production, this crop has been recently re-
evaluated in various industrial sectors. Until now, inflorescences have been considered a …

Introduction: Nausea and vomiting are the most distressing symptoms reported by oncology
patients undergoing anticancer treatment. With the currently available treatments, vomiting …

The plant Cannabis sativa contains more than 100 chemical compounds, known collectively
as phytocannabinoids. Four of these compounds, Δ9-and Δ8-tetrahydrocannabinol (Δ9-and …

As a remedy against stress and anxiety, cannabidiol (CBD) products are of increasing
interest in veterinary medicine. Limited data is available describing the actual effectiveness …

Introduction In the last two decades, our understanding of the therapeutic utility and
medicinal properties of cannabis has greatly changed. This change has been accompanied …

A growing body of experimental evidence strongly suggests that cannabidiolic acid (CBDA),
a major component of the fiber-type cannabis plant, exerts a variety of biological activities …

Cannabidiolic acid (CBDA) can activate peroxisome proliferator-activated receptor-α
(PPARα) and PPARγ. Whether CBDA can activate PPARβ/δ has not been examined …