Halloysite clay nanotubes for life sciences applications: From drug encapsulation to bioscaffold

AC Santos, C Ferreira, F Veiga, AJ Ribeiro… - Advances in colloid and …, 2018 - Elsevier
Natural forming clay halloysite is an emerging nanomaterial carrier for sustained drug
delivery. These 50 nm diameter aluminosilicate tubes, with inner-alumina and outer-silica …

[HTML][HTML] Nanomaterials: a review about halloysite nanotubes, properties, and application in the biological field

G Biddeci, G Spinelli, P Colomba, F Di Blasi - International Journal of …, 2022 - mdpi.com
The use of synthetic materials and the attention towards environmental hazards and toxicity
impose the development of green composites with natural origins. Clay is one of the …

Systematic studies on blood coagulation mechanisms of halloysite nanotubes-coated PET dressing as superior topical hemostatic agent

Y Feng, X Luo, F Wu, H Liu, E Liang, RR He… - Chemical Engineering …, 2022 - Elsevier
Halloysite nanotubes (HNTs), a traditional mineral Chinese medicine, have been used to
stop bleeding for thousands of years. However, the coagulation mechanisms of HNTs and …

ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment

W Muhammad, J Zhu, Z Zhai, J Xie, J Zhou, X Feng… - Acta biomaterialia, 2022 - Elsevier
The acute lung injury (ALI) is an inflammatory disorder associated with cytokine storm, which
activates various reactive oxygen species (ROS) signaling pathways and causes severe …

Evaluation of the effects of halloysite nanotube on polyhydroxybutyrate-chitosan electrospun scaffolds for cartilage tissue engineering applications

S Ghadirian, S Karbasi - International Journal of Biological Macromolecules, 2023 - Elsevier
Scaffolding method and material that mimic the extracellular matrix (ECM) of host tissue is
an integral part of cartilage tissue engineering. This study aims to enhance the properties of …

Halloysite nanotubes in analytical sciences and in drug delivery: A review

M Fizir, P Dramou, NS Dahiru, W Ruya, T Huang… - Microchimica Acta, 2018 - Springer
Halloysite (HNT) is a natural inorganic mineral that has many applications in manufacturing.
This review (with 192 references) covers (a) the chemical properties of halloysites,(b) the …

Enhanced therapeutic efficacy of doxorubicin for breast cancer using chitosan oligosaccharide-modified halloysite nanotubes

J Yang, Y Wu, Y Shen, C Zhou, YF Li… - ACS applied materials …, 2016 - ACS Publications
Halloysite nanotubes (HNTs) are natural aluminosilicates with unique hollow lumen
structure, also having high specific area, good biocompatibility, nontoxicity, and low price …

Effects of halloysite nanotubes on physical properties and cytocompatibility of alginate composite hydrogels

B Huang, M Liu, Z Long, Y Shen, C Zhou - Materials Science and …, 2017 - Elsevier
Sodium alginate (SA)/halloysite nanotubes (HNTs) composite hydrogels were successfully
prepared by solution blending and cross-linking with calcium ions. HNTs can improve the …

Folic acid-conjugated chitosan oligosaccharide-magnetic halloysite nanotubes as a delivery system for camptothecin

P Dramou, M Fizir, A Taleb, A Itatahine, NS Dahiru… - Carbohydrate …, 2018 - Elsevier
In this research, to achieve enhanced intracellular uptake of anticancer drug carriers for
efficient chemotherapy, folic acid conjugated chitosan oligosaccharides assembled …

Folate-conjugated halloysite nanotubes, an efficient drug carrier, deliver doxorubicin for targeted therapy of breast cancer

YP Wu, J Yang, HY Gao, Y Shen, L Jiang… - ACS Applied Nano …, 2018 - ACS Publications
To carry doxorubicin (DOX) on breast cancer site effectively, halloysite nanotubes
conjugated with poly (ethylene glycol) and folate (HNTs-PEG-FA) is designed as a targeted …