Preparation of astaxanthin‐loaded composite micelles with coaxial electrospray technology for enhanced oral bioavailability and improved antioxidation capability

Y Liao, H Wang, S Li, Y Xue, Y Chen… - Journal of the …, 2024 - Wiley Online Library
BACKGROUND Astaxanthin (AST) is approved by the US Food and Drug Administration
(FDA) as a safe dietary supplement for humans. As a potent lipid‐soluble keto‐carotenoid, it …

Moisture-induced limited recrystallization may not reduce the dissolution of amorphous solid dispersions: A case of nitrendipine

P Zhao, H Wang, J Jia, D Song, L Yang, X Tang… - Journal of Industrial and …, 2024 - Elsevier
As a promising strategy, amorphous solid dispersion (ASD) technology has been widely
studied and employed. However, moisture affects the physical stability of ASD, leading to …

Evaluation of microstructure, dissolution rate, and oral bioavailability of paclitaxel poloxamer 188 solid dispersion

Y Liu, Y Zhang, Q Yan, X Zhong, C Hu - Drug Delivery and Translational …, 2024 - Springer
Poor solubility is a major challenge for enhancing the oral bioavailability and clinical
application of many drugs, including the broad-spectrum chemotherapy drug paclitaxel …

Characterization and Dissolution Mechanism of Low-Molecular-Weight Organic Acids or Inorganic Mesoporous Particle-Based Piperine Amorphous Solid Dispersions

Y Li, Q Zhang, N Yu, L Peng, Q Gao, L Li, J Zhao… - Langmuir, 2024 - ACS Publications
The objective of the current study is to prepare amorphous solid dispersions (ASDs)
containing piperine (PIP) by utilizing organic acid glycyrrhizic acid (GA) and inorganic …