[HTML][HTML] Dendrimers in the context of nanomedicine
AP Dias, S da Silva Santos, JV da Silva… - International journal of …, 2020 - Elsevier
Dendrimers are globular structures, presenting an initiator core, repetitive layers starting
radially from the core and terminal groups on the surface, resembling tree architecture …
radially from the core and terminal groups on the surface, resembling tree architecture …
[HTML][HTML] Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures
Background Skin cancer has been the leading type of cancer worldwide. Melanoma and
non-melanoma skin cancers are now the most common types of skin cancer that have been …
non-melanoma skin cancers are now the most common types of skin cancer that have been …
Nanoparticles for topical drug delivery: Potential for skin cancer treatment
V Krishnan, S Mitragotri - Advanced Drug Delivery Reviews, 2020 - Elsevier
Nanoparticles offer new opportunities for the treatment of skin diseases. The barrier function
of the skin poses a significant challenge for nanoparticles to permeate into the tissue …
of the skin poses a significant challenge for nanoparticles to permeate into the tissue …
Dendrimers as efficient nanocarriers for the protection and delivery of bioactive phytochemicals
The genesis of dendrimers can be considered as a revolution in nano-scaled bioactive
delivery systems. These structures possess a unique potential in encapsulating/entrapping …
delivery systems. These structures possess a unique potential in encapsulating/entrapping …
Dendrimer nanotherapy for severe COVID-19 attenuates inflammation and neurological injury markers and improves outcomes in a phase2a clinical trial
AM Gusdon, N Faraday, JS Aita, S Kumar… - Science translational …, 2022 - science.org
Hyperinflammation triggered by SARS-CoV-2 is a major cause of disease severity, with
activated macrophages implicated in this response. OP-101, a hydroxyl-polyamidoamine …
activated macrophages implicated in this response. OP-101, a hydroxyl-polyamidoamine …
[HTML][HTML] Targeting mitochondrial dysfunction and oxidative stress in activated microglia using dendrimer-based therapeutics
Mitochondrial oxidative stress is associated with many neurodegenerative diseases, such as
traumatic brain injury (TBI). Targeted delivery of antioxidants to mitochondria has failed to …
traumatic brain injury (TBI). Targeted delivery of antioxidants to mitochondria has failed to …
Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma
Glioblastoma is among the most aggressive forms of cancers, with a median survival of just
15–20 months for patients despite maximum clinical intervention. The majority of …
15–20 months for patients despite maximum clinical intervention. The majority of …
Dendrimer mediated targeted delivery of sinomenine for the treatment of acute neuroinflammation in traumatic brain injury
Traumatic brain injury (TBI) is a significant medical problem with limited treatment options
and is one of the main causes of life-long disability. Neuroinflammation orchestrated by …
and is one of the main causes of life-long disability. Neuroinflammation orchestrated by …
Dendrimers, an emerging opportunity in personalized medicine?
AM Caminade - Journal of personalized medicine, 2022 - mdpi.com
Dendrimers are highly branched macromolecules tailorable at will to fulfil precise
requirements. They have generated a great many expectations and a huge number of …
requirements. They have generated a great many expectations and a huge number of …
Potential of nano-antioxidants and nanomedicine for recovery from neurological disorders linked to long COVID syndrome
T Akanchise, A Angelova - Antioxidants, 2023 - mdpi.com
Long-term neurological complications, persisting in patients who cannot fully recover
several months after severe SARS-CoV-2 coronavirus infection, are referred to as …
several months after severe SARS-CoV-2 coronavirus infection, are referred to as …