Gold nanoparticles for cancer radiotherapy: a review

K Haume, S Rosa, S Grellet, MA Śmiałek… - Cancer …, 2016 - Springer
Radiotherapy is currently used in around 50% of cancer treatments and relies on the
deposition of energy directly into tumour tissue. Although it is generally effective, some of the …

Radiosensitizing high-Z metal nanoparticles for enhanced radiotherapy of glioblastoma multiforme

J Choi, G Kim, SB Cho, HJ Im - Journal of Nanobiotechnology, 2020 - Springer
Radiotherapy is an essential step during the treatment of glioblastoma multiforme (GBM),
one of the most lethal malignancies. The survival in patients with GBM was improved by the …

Biological mechanisms of gold nanoparticle radiosensitization

S Rosa, C Connolly, G Schettino, KT Butterworth… - Cancer …, 2017 - Springer
There has been growing interest in the use of nanomaterials for a range of biomedical
applications over the last number of years. In particular, gold nanoparticles (GNPs) possess …

Role of omics techniques in the toxicity testing of nanoparticles

E Fröhlich - Journal of nanobiotechnology, 2017 - Springer
Nanotechnology is regarded as a key technology of the twenty-first century. Despite the
many advantages of nanotechnology it is also known that engineered nanoparticles (NPs) …

Colloidal gold nanoparticles induce changes in cellular and subcellular morphology

X Ma, R Hartmann, D Jimenez de Aberasturi, F Yang… - ACS …, 2017 - ACS Publications
Exposure of cells to colloidal nanoparticles (NPs) can have concentration-dependent
harmful effects. Mostly, such effects are monitored with biochemical assays or probes from …

Mechanistic insights into the biological effects of engineered nanomaterials: A focus on gold nanoparticles

NHA Nguyen, P Falagan-Lotsch - International Journal of Molecular …, 2023 - mdpi.com
Nanotechnology has great potential to significantly advance the biomedical field for the
benefit of human health. However, the limited understanding of nano–bio interactions …

At the Crossroads of Nanotoxicology in vitro: Past Achievements and Current Challenges

SM Hussain, DB Warheit, SP Ng… - Toxicological …, 2015 - academic.oup.com
The exponential growth in the employment of nanomaterials (NMs) has given rise to the field
of nanotoxicology; which evaluates the safety of engineered NMs. Initial nanotoxicological …

Cross-correlative single-cell analysis reveals biological mechanisms of nanoparticle radiosensitization

T Turnbull, M Douglass, NH Williamson, D Howard… - ACS …, 2019 - ACS Publications
Nanoparticle radiosensitization has been demonstrated well to enhance the effects of
radiotherapy, motivate the improvement of therapeutic ratios, and decrease morbidity in …

Significance and nature of bystander responses induced by various agents

N Verma, AB Tiku - Mutation Research/Reviews in Mutation Research, 2017 - Elsevier
Bystander effects in a biological system are the responses shown by non-targeted
neighbouring cells/tissues/organisms. These responses are triggered by factors released …

Analytical aspects of nanotoxicology

IL Gunsolus, CL Haynes - Analytical chemistry, 2016 - ACS Publications
Nanotoxicology, the study of nanomaterial toxicity to biological systems, has become a
vibrant area of research over the past 10 years. Two main factors drive this enthusiasm:(1) …