Accurate diagnosis of human diseases is crucial for effective prevention, clinical treatment,
and prognosis. The World Health Organization (WHO) has provided guidelines for molecular …

Nucleic acid detection powered by CRISPR technology provides a rapid, sensitive, and
deployable approach to molecular diagnostics. While exciting, there remain challenges …

Recently, a wide spectrum of artificial intelligence (AI)–based applications in the broader
categories of digital pathology, biomarker development, and treatment have been explored …

The trans-cleavage activity of CRISPR/Cas12a has been widely used in biosensing.
However, many CRISPR/Cas12a-based biosensors, especially those that work in “on–off …

As CRISPR technology is promoted to more fine-divided molecular biology applications, its
inherent performance finds it increasingly difficult to cope with diverse needs in these …

Recently, field‐effect transistors (FETs) have emerged as a novel type of multiparameter,
high‐performance, highly integrated platform for biochemical detection, leveraging their …

The CRISPR‐Cas12a system has emerged as a powerful tool for next‐generation nucleic
acid‐based molecular diagnostics. However, it has long been believed to be effective only …

Gene point mutations play a significant role in the development of cancer. Therefore,
developing a sensitive, specific, and universally applicable method for detecting gene point …

Cas14a may recognize and randomly cleave ssDNAs without protospacer adjacent motif
(PAM) sequence restriction to benefit nucleic acid sensing. However, the sensitivity of …

The integration of recombinase polymerase amplification (RPA) with CRISPR/Cas
technology has revolutionized molecular diagnostics and pathogen detection due to its …