Contingent stimulus delivery assay for zebrafish reveals a role for CCSER1 in alcohol preference

FM Nathan, C Kibat, T Goel, J Stewart… - Addiction …, 2022 - Wiley Online Library
Alcohol use disorders are complex, multifactorial phenomena with a large footprint within the
global burden of diseases. Here, we report the development of an accessible, two‐choice …

Melanin-concentrating hormone receptor 1 (MCH1-R) antagonism: reduced appetite for calories and suppression of addictive-like behaviors

C Karlsson, M Zook, R Ciccocioppo, DR Gehlert… - Pharmacology …, 2012 - Elsevier
RATIONALE: The hypothalamic neuropeptide melanin-concentrating hormone and its
MCH1 receptor have been implicated in regulation of feeding and energy homeostasis, as …

Behavioral and neurobiological consequences of hedonic feeding on alcohol drinking

J Brutman, JF Davis, S Sirohi - Current pharmaceutical design, 2020 - ingentaconnect.com
A complex interplay of peripheral and central signaling mechanisms within the body of an
organism maintains energy homeostasis. In addition, energy/food intake is modified by …

Adolescent binge-like ethanol exposure reduces basal α-MSH expression in the hypothalamus and the amygdala of adult rats

JM Lerma-Cabrera, F Carvajal, M Alcaraz-Iborra… - Pharmacology …, 2013 - Elsevier
Melanocortins (MC) are central peptides that have been implicated in the modulation of
ethanol consumption. There is experimental evidence that chronic ethanol exposure …

Stimulation of nicotine reward and central cholinergic activity in Sprague–Dawley rats exposed perinatally to a fat-rich diet

I Morganstern, O Lukatskaya, SH Moon, WR Guo… - …, 2013 - Springer
Rationale While clinical studies show maternal consumption of palatable fat-rich diets during
pregnancy to negatively impact the children's behaviors and increase their vulnerability to …

Involvement of activated brain stress responsive systems in excessive and “relapse” alcohol drinking in rodent models: implications for therapeutics

Y Zhou, MJ Kreek - Journal of Pharmacology and Experimental …, 2018 - ASPET
Addictive diseases, including addiction to alcohol, pose massive public health costs.
Addiction is a chronic relapsing disease caused by both the direct effects induced by drugs …

Effects of glucagon-like peptide-1 receptor agonists on fluid intake in healthy volunteers

B Winzeler, I da Conceição, J Refardt, CO Sailer… - Endocrine, 2020 - Springer
Abstract Purpose Glucagon-like peptide-1 (GLP-1) receptor agonists (RA) reduce appetite
and energy intake. Recent findings from animal studies suggest a role of GLP-1 in drinking …

Orexin in patients with alcohol dependence treated for relapse prevention: a pilot study

M Ziółkowski, D Czarnecki, J Budzyński… - Alcohol and …, 2016 - academic.oup.com
Aim The aim of the study was to assess the blood concentration of orexin and its association
with other clinical factors in patients with alcohol dependence. Methods Thirty-two males …

Космос. Радиация. Человек (Радиационный барьер в межпланетных полетах)

ИБ Ушаков - 2021 - elibrary.ru
Главный барьер дальнейшего проникновения человека в космос-радиация различных
источников: галактические и солнечные космические лучи. Смоделировать всё на …

Binge-like intake of HFD attenuates alcohol intake in rats

S Sirohi, A Van Cleef, JF Davis - Physiology & behavior, 2017 - Elsevier
Binge eating and binge alcohol intake are behavioral manifestations of pathological feeding
and alcohol use disorder (AUD), respectively. Binge-feeding and AUD have high …