Neutrophils have been extensively described in the pathophysiology of autoimmune and
infectious diseases. Accumulating evidence also suggests the important role of neutrophils …

The role of neutrophils in solid tumor metastasis remains largely controversial. In preclinical
models of solid tumors, both pro-metastatic and anti-metastatic effects of neutrophils have …

Background: Melanoma is highly immunogenic and therefore suitable for immunotherapy,
but the efficacy is limited by response rate. In several types of tumor, tumor mutation burden …

Neutrophil-to-lymphocyte ratio (NLR) serves as a strong prognostic indicator for patients
suffering from various diseases. Neutrophil activation promotes the recruitment of a number …

The neutrophil-to-lymphocyte ratio (NLR) is gaining traction as a biomarker with utility in a
variety of malignancies including melanoma. Intact lymphocyte function is necessary for …

Background An elevated neutrophil‐to‐lymphocyte ratio (NLR) is associated with poor
survival in patients with cancer, including those who receive immunotherapies. The authors …

Background The systemic immune‐inflammation index (SII) is correlated with patient
survival in various types of solid tumors. However, only a few studies have focused on the …

Objective The study objective was to investigate the use of peripheral blood biomarkers as
predictors of patient survival. The aim of this study was to identify the baseline peripheral …

Determining the prognostic association of different immune cell types in the tumor
microenvironment is critical for understanding cancer biology and developing new …

It has been recognized that systemic inflammatory markers (SIMs) are associated with
patient survival in various types of cancer. This study aimed to determine the optimal cut-off …